Evidence map›Paper›PMID 34589819›Full record

ArticleBrain, behavior, & immunity - health2021

A pilot [

Judith D Schaechter, Baileigh G Hightower, Minhae Kim, Marco L Loggia

Open access · goldAbstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Immunologic Underpinnings of Post-Stroke Depression.Biological psychiatry global open science · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Pathomechanisms of Vascular Depression in Older Adults.International journal of molecular sciences · 2021
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Judith D SchaechterAthinoula A. Martinos Center for Biomedical Imaging Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 13th Street, Building 149, Room 2301, Charlestown, MA, 02129, USA.
Baileigh G HightowerAthinoula A. Martinos Center for Biomedical Imaging Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 13th Street, Building 149, Room 2301, Charlestown, MA, 02129, USA.
Minhae KimAthinoula A. Martinos Center for Biomedical Imaging Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 13th Street, Building 149, Room 2301, Charlestown, MA, 02129, USA.
Marco L LoggiaAthinoula A. Martinos Center for Biomedical Imaging Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 13th Street, Building 149, Room 2301, Charlestown, MA, 02129, USA.
Harvard University · US

Funding

Carbon-11 Automation Equipment for Human PET Radiotracer ProductionS10OD023517 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI HOOKER, JACOB M. · 2018 to 2018
$502k
A Study of Neuroimmune Mechanisms of Poststroke Fatigue using Integrated PET/MRIR21NS110982 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI LOGGIA, MARCO LUCIANO, SCHAECHTER, JUDITH DIANE · 2019 to 2019
$462k
NIH HHS S10 OD023517NINDS NIH HHS R21 NS110982
6 · The paper itself

Abstract

Neuroinflammation occurs in response to acute ischemic stroke, and has been speculated to underlie secondary poststroke pathologies, such as depression, that often develop over time poststroke. However, no study has examined whether neuroinflammation is present in chronic stroke patients (e.g., ​≥ ​1 year poststroke). This study tested whether neuroinflammation is present in chronic stroke patients, and is associated with neurodegeneration, using [

Indexed as

Activated gliaIschemiaMicrogliaMiddle cerebral arteryTSPO

Identifiers

PMID34589819
PMCPMC8474408
OpenAlexW3195966762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.