Evidence map›Paper›PMID 34589777›Full record

ArticleBrain, behavior, & immunity - health2021

Continued Underutilization of stroke care during the COVID-19 pandemic.

Sen Sheng, Xixi Wang, Carolina Gil Tommee, Naren Arulprakash, Mudassar Kamran, Vishank Shah, Madhu Jasti, Sisira Yadala, Aliza Brown, Sanjeeva Onteddu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sen ShengDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Xixi WangDepartment of Mathematics and Statistics, University of Arkansas in Little Rock, Little Rock, AR, USA.
Carolina Gil TommeeDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Naren ArulprakashDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Mudassar KamranDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Vishank ShahDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Madhu JastiUniversity of Maryland, Baltimore Washington Medical Center, USA.
Sisira YadalaDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Aliza BrownDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Sanjeeva OntedduDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Krishna NalleballeDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
University of Arkansas for Medical Sciences · USUniversity of Arkansas at Little Rock · USUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to investigate the utilization of acute ischemic stroke (AIS) services during the Corona Virus Disease 2019 (COVID-19) pandemic. Based on early observations among healthcare utilization on stroke and other healthcare services, we hypothesized that there would be a persistent significant decline in AIS patients presenting to hospitals as the pandemic has progressed for over a year.

methodTriNetX, a large research network, is used to collect real-time electronic medical data. Data on utilization of acute ischemic stroke service was collected for the years 2018, 2019, and 2020 for variables including overall stroke volume and the number of patients that received intravenous tissue plasminogen activator (tPA) and mechanical thrombectomy (MT).

resultWe found a 13.2-15.4% decrease in total number of AIS patients in 2020 (n 77231) compared with the years 2018 and 2019 (n 88948 and 91270 respectively, p ​< ​0.001). In the year 2020 Stroke volume was significantly lower in Q4 comparing to Q1 (Q1 vs Q4, p ​< ​0.01, while there were no significant differences in stroke volume between Quarters 2, 3, and 4 in 2020 (Q2 vs Q3, p ​= ​0.39, Q2 vs Q4, p ​= ​0.61, Q3 vs Q4, p ​= ​0.18). The Proportion of patients receiving tPA in 2020 was significantly lower compared to prior years (5.4% in 2020 vs 6.4% in 2018 and 6.0% in 2019,

conclusionDespite significant alteration in practices to optimize healthcare delivery and mitigate the collateral impact of the pandemic on care for other conditions, a persistent decline in AIS volumes remains. Delayed presentation, fear-of-contagion, reallocation, and poor availability of health care resources are potential contributors. Prospective evaluation and further investigation for these trends is needed.

Indexed as

Acute ischemic strokeCOVID-19Healthcare utilizationMechanical thrombectomy (MT)Tissue plasminogen activator (tPA)

Identifiers

PMID34589777
PMCPMC8474631
OpenAlexW3161018986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.