Evidence map›Paper›PMID 34589769›Full record

ArticleBrain, behavior, & immunity - health2021

BK polyomavirus associated progressive multifocal leukoencephalopathy in a person living with HIV.

Brendan O'Kelly, Amy Keane, Emma Devitt, Andrew Lockhart, Deirdre O'Rourke, Fiona Lyons

Open access · goldAbstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. BK and JC polyomavirus co-infection resulting in polyomavirus nephropathy and progressive multifocal leukoencephalopathy at the same time, a case report.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Brendan O'KellyGenitourinary Medicine and Infectious Diseases Department (GUIDe), St James's Hospital, Dublin 8, Ireland.
Amy KeaneGenitourinary Medicine and Infectious Diseases Department (GUIDe), St James's Hospital, Dublin 8, Ireland.
Emma DevittGenitourinary Medicine and Infectious Diseases Department (GUIDe), St James's Hospital, Dublin 8, Ireland.
Andrew LockhartNeurology Department St James's Hospital, Dublin 8, Ireland.
Deirdre O'RourkeNeurology Department St James's Hospital, Dublin 8, Ireland.
Fiona LyonsGenitourinary Medicine and Infectious Diseases Department (GUIDe), St James's Hospital, Dublin 8, Ireland.
St. James's Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the white matter central nervous system occurring in immunocompromised patients particularly those with T cell deficiency such as in HIV, haematological and solid organ malignancies and those taking immunomodulatory medications. PML is caused by JC virus however in rare cases BK virus has been isolated in the cerebral spinal fluid of patients presenting with PML. In this case we describe a 49 year old man who presented to the emergency department with a 2 week history of progressive right sided weakness and dysarthria. His background history included HIV diagnosed in 2005, he had not engaged with care in the past 2 years and had not been taking anti-retroviral therapy (ART). Other past medical history included untreated hepatitis C. His CD4 count was 90 (11%) cells/mm

Indexed as

BK virusHIVImmune reconstitution inflammatory syndromeProgressive multifocal leukoencephalopathy

Identifiers

PMID34589769
PMCPMC8474382
OpenAlexW3158140286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.