Amyotrophic lateral sclerosis in a patient who recovered from Miller Fisher Syndrome: The role of GQ1b antibody revisited.

Michael Repajic, Syed Husain, Azadeh Ghassemi, Manvel Kondradzhyan, Antonio Liu

Open access · goldAbstract readCase Reports

In one paragraph

Article in Brain, behavior, & immunity - health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.2field-weighted citation impact, top 46% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael RepajicNeurology, Adventist Health White Memorial, Los Angeles, CA, USA.

Syed HusainNeurology, Adventist Health White Memorial, Los Angeles, CA, USA.

Azadeh GhassemiInternal Medicine, Connecticut Institute for Communities, Danbury, CT, USA.

Manvel KondradzhyanNeurology, Adventist Health White Memorial, Los Angeles, CA, USA.

Antonio LiuNeurology, Adventist Health White Memorial, Los Angeles, CA, USA.

White Memorial Medical Center · USInstitute for Community Living · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Miller Fisher Syndrome (MFS), a variant of Guillain Barre Syndrome (GBS), and amyotrophic lateral sclerosis (ALS) are two rare neuromuscular diseases that are usually unrelated. While ganglioside antibodies have a common relation with MFS and GBS, they have also been found in association, albeit less commonly, with ALS. A patient experiencing MFS and then ALS in tandem has never been documented. We discuss a case demonstrating these findings, with GQ1b elevated on both occasions. The pathophysiologic role of GQ1b is explored.

Indexed as

Amyotrophic lateral sclerosisGanglioside antibodiesGQ1bMiller Fisher syndrome

Identifiers

PMID34589746

DOI10.1016/j.bbih.2021.100231

PMCPMC8474546

OpenAlexW3134783781

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.