Evidence map›Paper›PMID 34589730›Full record

ArticleBrain, behavior, & immunity - health2021

Toxoplasma gondii seropositivity in patients with depressive and anxiety disorders.

Nienke J de Bles, Juliette E H van der Does, Laetitia M Kortbeek, Agnetha Hofhuis, Gerard van Grootheest, Albert M Vollaard, Robert A Schoevers, Albert M van Hemert, Brenda W J H Penninx, Nathaly Rius-Ottenheim and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  6. Impact ofJournal of clinical medicine · 2024
    Review
  7. Chronic infection by atypicalBrain, behavior, & immunity - health · 2023
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Nienke J de BlesDepartment of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.
Juliette E H van der DoesDepartment of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.
Laetitia M KortbeekNational Institute for Public Health and the Environment (RIVM), Centre for Disease Control the Netherlands, Bilthoven, the Netherlands.
Agnetha HofhuisNational Institute for Public Health and the Environment (RIVM), Centre for Disease Control the Netherlands, Bilthoven, the Netherlands.
Gerard van GrootheestDepartment of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.
Albert M VollaardNational Institute for Public Health and the Environment (RIVM), Centre for Disease Control the Netherlands, Bilthoven, the Netherlands.
Robert A SchoeversDepartment of Psychiatry, University Medical Center Groningen, Groningen, the Netherlands.
Albert M van HemertDepartment of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.
Brenda W J H PenninxDepartment of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.
Nathaly Rius-OttenheimDepartment of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.
Erik J GiltayDepartment of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.
Leiden University Medical Center · NLNational Institute for Public Health and the Environment · NLAmsterdam University Medical Centers · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction

methodsIn the Netherlands Study of Depression and Anxiety (NESDA),

resultsParticipants were on average 51.2 years (

conclusionsNo evidence was found for a relationship between affective disorders and

Indexed as

AnxietyCognitive reactivityDepressionSuicidalityToxoplasma gondii

Identifiers

PMID34589730
PMCPMC8474384
OpenAlexW3117033311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.