Evidence map›Paper›PMID 34589503›Full record

ArticleFrontiers in medicine2021

An Individual Patient's "Body" on Chips-How Organismoid Theory Can Translate Into Your Personal Precision Therapy Approach.

Uwe Marx, Enrico Accastelli, Rhiannon David, Hendrik Erfurth, Leopold Koenig, Roland Lauster, Anja Patricia Ramme, Petra Reinke, Hans-Dieter Volk, Annika Winter and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Uwe MarxDepartment of Medical Biotechnology, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.
Enrico AccastelliTissUse GmbH, Berlin, Germany.
Rhiannon DavidFunctional and Mechanistic Safety, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge, United Kingdom.
Hendrik ErfurthTissUse GmbH, Berlin, Germany.
Leopold KoenigTissUse GmbH, Berlin, Germany.
Roland LausterDepartment of Medical Biotechnology, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.
Anja Patricia RammeTissUse GmbH, Berlin, Germany.
Petra ReinkeBerlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Hans-Dieter VolkBIH-Center for Regenerative Therapies, Berlin Institute of Health, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Annika WinterTissUse GmbH, Berlin, Germany.
Eva-Maria DehneTissUse GmbH, Berlin, Germany.
Technische Universität Berlin · DEAstraZeneca (United Kingdom) · GBBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DECharité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first concepts for reproducing human systemic organismal biology

Indexed as

advanced therapiesimmune-oncologymicrophysiological systemsorganismoidorganoidorgan-on-chippatient-on-chipreal world data

Identifiers

PMID34589503
PMCPMC8473633
OpenAlexW3200416417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.