Evidence map›Paper›PMID 34589442›Full record

ArticleFrontiers in cellular and infection microbiology2021

Aerobactin Seems To Be a Promising Marker Compared With Unstable RmpA2 for the Identification of Hypervirulent Carbapenem-Resistant

Chaitra Shankar, Soumya Basu, Binesh Lal, Sathiya Shanmugam, Karthick Vasudevan, Purva Mathur, Sudha Ramaiah, Anand Anbarasu, Balaji Veeraraghavan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. A systematic review of hypervirulentFrontiers in medicine · 2025
    Pooled it
  3. Article
  4. Article
  5. The genomic landscape of Klebsiella pneumoniae in Russia.World journal of microbiology & biotechnology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Multiplex PCR assay for the rapid detection ofJournal of medical microbiology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Multidrug-resistant hypervirulentFuture microbiology · 2025
    Review
  16. Characterization of OXA232-Producing Carbapenem-ResistantPolish journal of microbiology · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chaitra ShankarDepartment of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.
Soumya BasuMedical & Biological Computing Laboratory, School of Biosciences & Technology, Vellore Institute of Technology, Vellore, India.
Binesh LalDepartment of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.
Sathiya ShanmugamDepartment of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.
Karthick VasudevanDepartment of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.
Purva MathurDepartment of Laboratory Medicine, Jai Prakash Narayan Apex, Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.
Sudha RamaiahMedical & Biological Computing Laboratory, School of Biosciences & Technology, Vellore Institute of Technology, Vellore, India.
Anand AnbarasuMedical & Biological Computing Laboratory, School of Biosciences & Technology, Vellore Institute of Technology, Vellore, India.
Balaji VeeraraghavanDepartment of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.
Christian Medical College & Hospital · INVellore Institute of Technology University · INAll India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The incidence of hypervirulent (hv) carbapenem-resistant (CR) Methods: Twenty-seven CRKp isolates were identified to possess Results: The CR-hvKp belonged to multidrug-resistant (MDR) high-risk clones such as CG11, CG43, ST15, and ST231 and carried OXA-232 as the predominant carbapenemase followed by NDM. The virulence plasmid belonged to IncHI1B replicon type and carried frameshifted and truncated Conclusion: Increasing incidence of convergence of AMR and virulence is observed among

Indexed as

Klebsiella InfectionsKlebsiella pneumoniaeCarbapenemsComputer SimulationHumansHydroxamic AcidsaerobactinCarbapenemsHydroxamic Acidsaerobactincarbapenem resistancehypervirulentKlebsiella pneumoniaeOXA-232rmpA2stabilitystructure

Identifiers

PMID34589442
PMCPMC8473682
OpenAlexW3200900898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.