Evidence map›Paper›PMID 34589432›Full record

ArticleFrontiers in oncology2021

Comprehensive Clinicopathologic and Molecular Analysis of Mast Cell Leukemia With Associated Hematologic Neoplasm: A Report and In-Depth Study of 5 Cases.

Philippa Li, Giulia Biancon, Timil Patel, Zenggang Pan, Shalin Kothari, Stephanie Halene, Thomas Prebet, Mina L Xu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Philippa LiDepartment of Pathology, Yale School of Medicine, New Haven, CT, United States.
Giulia BianconSection of Hematology, Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven, CT, United States.
Timil PatelSection of Hematology, Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven, CT, United States.
Zenggang PanDepartment of Pathology, Yale School of Medicine, New Haven, CT, United States.
Shalin KothariSection of Hematology, Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven, CT, United States.
Stephanie HaleneSection of Hematology, Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven, CT, United States.
Thomas PrebetSection of Hematology, Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven, CT, United States.
Mina L XuDepartment of Pathology, Yale School of Medicine, New Haven, CT, United States.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Mast cell leukemia with associated hematologic neoplasm (MCL-AHN) is a rare and highly aggressive entity that remains understudied due to the paucity of cases. We present a case of a 45-year-old man who was concurrently diagnosed with mast cell leukemia and acute myeloid leukemia. We identified four additional patients who had MCL-AHN in our institution and performed whole-exome sequencing of all available tumors. Our series revealed a novel and identical

Indexed as

acute myeloid leukemiaassociated hematologic neoplasmmast cell leukemiasystemic mastocytosis (SM)whole-exome sequencing

Identifiers

PMID34589432
PMCPMC8474637

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.