Evidence map›Paper›PMID 34589256›Full record

ArticleTurk gogus kalp damar cerrahisi dergisi2021

Positron emission tomography/computed tomography findings of lung invasive adenocarcinoma subgroups and comparison of their short-term survivals.

Bahar Ağaoğlu Şanlı, Fatma İlknur Ulugün, Volkan Karaçam, Duygu Gürel, Recep Bekiş, Aydın Şanlı, Nezih Özdemir

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Article in Turk gogus kalp damar cerrahisi dergisi, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Bahar Ağaoğlu ŞanlıDepartment of Thoracic Surgery, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey.ORCID 0000-0001-8462-6059
Fatma İlknur UlugünDepartment of Thoracic Surgery, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey.ORCID 0000-0002-3383-4832
Volkan KaraçamDepartment of Thoracic Surgery, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey.ORCID 0000-0003-2505-7276
Duygu GürelDepartment of Pathology, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey.ORCID 0000-0002-1992-7338
Recep BekişDepartment of Nuclear Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.ORCID 0000-0002-8313-8974
Aydın ŞanlıDepartment of Thoracic Surgery, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey.ORCID 0000-0002-2999-9642
Nezih ÖzdemirDepartment of Thoracic Surgery, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey.ORCID 0000-0003-3086-8284

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to compare the maximum standardized uptake values on positron emission tomography/ computed tomography and survival of lung invasive adenocarcinoma subgroups.

methodsBetween January 2010 and January 2016, a total of 152 patients (112 males, 40 females; mean age: 64.2±8.6 years; range, 41 to 88 years) who underwent lung resection for an invasive adenocarcinoma were retrospectively analyzed. The patients were divided into subgroups as follows: acinar, lepidic, micropapillary, papillary, and solid. The maximum standardized uptake values in the imaging study and their relationship with survival were examined.

resultsThere were 84 acinar (55%), 31 solid (20%), 23 lepidic (15%), nine papillary (5%), and five micropapillary (3%) cases. The positron emission tomography/computed tomography enhancement showed a statistically significant difference among the subgroups (p=0.004). The solid subgroup was the most involved (9.76), followed by micropapillary (8.98), acinar (8.06), papillary (5.82), and lepidic (4.23) subgroups, respectively. According to Tumor, Node, Metastasis staging, Stage I was present in 48.68% (n=74) of the cases, Stage II in 25.0% (n=38), Stage III in 25.0% (n=38), and Stage IV in 1.31% (n=2). The one-year, three-year, and five-year survival rates were significantly different among the disease stages (p=0.01). The longest survival duration was in the lepidic subgroup, although it did not reach statistical significance among the subgroups (p=0.587).

conclusionThe evaluation of invasive adenocarcinomas based on maximum standardized uptake values provides valuable information and may guide neoadjuvant and adjuvant therapies in the future.

Indexed as

Classificationcomputed tomographylung adenocarcinomapositron emission tomographysurvival

Identifiers

PMID34589256
PMCPMC8462100

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