Evidence map›Paper›PMID 34589204›Full record

Trial reportJournal of nutritional science2021

Effect of inulin-type fructans on appetite in patients with type 2 diabetes: a randomised controlled crossover trial.

Eline Birkeland, Sedegheh Gharagozlian, Kåre I Birkeland, Oda K S Holm, Per M Thorsby, Anne-Marie Aas

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of nutritional science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eline BirkelandSection of Nutrition and Dietetics, Department of Clinical Service, Division of Medicine, Oslo University Hospital, Oslo, Norway.
Sedegheh GharagozlianSection of Nutrition and Dietetics, Department of Clinical Service, Division of Medicine, Oslo University Hospital, Oslo, Norway.
Kåre I BirkelandFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Oda K S HolmDepartment of Nutrition, Faculty of Medicine, University of Oslo, Oslo, Norway.
Per M ThorsbyHormone Laboratory, Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
Anne-Marie AasSection of Nutrition and Dietetics, Department of Clinical Service, Division of Medicine, Oslo University Hospital, Oslo, Norway.
Oslo University Hospital · NOUniversity of Oslo · NO

Funding

Neuronal ensembles of drug context-induced impulsive decision makingR21DA036660 · NIDA · WASHINGTON STATE UNIVERSITY · PI FUCHS LOKENSGARD, RITA A, XIE, XIAOHU · 2014 to 2015
$425k
NIDA NIH HHS R21 DA036660
6 · The paper itself

Abstract

The aim of the study was to investigate the effect of prebiotic fibres on appetite-regulating hormones, subjective feeling of appetite and energy intake in subjects with type 2 diabetes. Data presented are secondary outcomes of a study investigating the effect of prebiotics on glucagon-like peptide-1 and glycaemic regulation. We conducted a randomised and placebo-controlled crossover trial to evaluate the effects of 16 g/d of inulin-type fructans or a control supplement (maltodextrin) for 6 weeks in randomised order, with a 4-week washout period in-between, on appetite in thirty-five men and women with type 2 diabetes. Data were collected at visits before and after each treatment: plasma concentration of the satiety-related peptides ghrelin and peptide YY (PYY) were assessed during a standardised mixed meal. The subjective sensation of appetite was evaluated in response to an

Indexed as

AppetiteDiabetes Mellitus, Type 2PrebioticsCross-Over StudiesFemaleGhrelinHumansInulinMalePeptide YYProspective StudiesSatiationGhrelinInulinPeptide YYPrebioticsDiabetes type 2GhrelinGLP-1, glucagon-like peptide-1ITF, inulin-type fructansPrebioticsPYYPYY, peptide YYStandardised mixed mealVAS, visual analogue scale

Identifiers

PMID34589204
PMCPMC8453458
OpenAlexW3199694953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.