Evidence map›Paper›PMID 34589084›Full record

ArticleFrontiers in immunology2021

Effects of Combinatorial Ubiquitinated Protein-Based Nanovaccine and STING Agonist in Mice With Drug-Resistant and Metastatic Breast Cancer.

Fang Huang, Ning Pan, Yiting Wei, Jinjin Zhao, Mohanad Aldarouish, Xuru Wang, Xiaotong Sun, Zhifa Wen, Yongqiang Chen, Lixin Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Fang HuangDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Ning PanDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Yiting WeiDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Jinjin ZhaoDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Mohanad AldarouishDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Xuru WangDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Xiaotong SunDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Zhifa WenDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Yongqiang ChenDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Lixin WangDepartment of Microbiology and Immunology, Medical School of Southeast University, Nanjing, China.
Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported that enriched ubiquitinated proteins (UPs) from tumor cells have the potential to be used as immunotherapy vaccine against cancer. Here we enriched UPs from epirubicin (EPB)-induced multi-drug-resistant cancer stem-like breast cancer cell line (4T1/EPB) and tested the efficacy of α-Al

Indexed as

AnimalsAntigens, NeoplasmAntineoplastic Combined Chemotherapy ProtocolsBreast NeoplasmsCancer VaccinesDrug Resistance, NeoplasmFemaleMembrane ProteinsMiceMice, Inbred BALB CNeoplastic Stem CellsSTING ProteinUbiquitinated ProteinsXanthonesAntigens, NeoplasmCancer VaccinesMembrane ProteinsSting1 protein, mouseSTING ProteinUbiquitinated ProteinsvadimezanXanthonesbreast cancercancer vaccinesSTING agonistubiquitinated proteinsα-Al2O3 nanoparticles

Identifiers

PMID34589084
PMCPMC8475273
OpenAlexW3201193908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.