Evidence map›Paper›PMID 34589063›Full record

ArticleFrontiers in microbiology2021

Repurposing Candesartan Cilexetil as Antibacterial Agent for MRSA Infection.

Lanlan Xu, Pengfei She, Lihua Chen, Shijia Li, Linying Zhou, Zubair Hussain, Yaqian Liu, Yong Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Drug Repurposing: An Emerging Strategy inJournal of microbiology and biotechnology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lanlan XuDepartment of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Pengfei SheDepartment of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Lihua ChenDepartment of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Shijia LiDepartment of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Linying ZhouDepartment of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Zubair HussainDepartment of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Yaqian LiuDepartment of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Yong WuDepartment of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Third Xiangya Hospital · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antibacterialbiofilmcandesartan cilexetilmembranepersistersresistanceStaphylococcus aureussynergistic

Identifiers

PMID34589063
PMCPMC8473943
OpenAlexW3200664091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.