Evidence map›Paper›PMID 34589049›Full record

ArticleFrontiers in neurology2021

Seizure Susceptibility Prediction in Uncontrolled Epilepsy.

Nhan Duy Truong, Yikai Yang, Christina Maher, Levin Kuhlmann, Alistair McEwan, Armin Nikpour, Omid Kavehei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nhan Duy TruongAustralian Research Council Training Centre for Innovative BioEngineering, School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Sydney, NSW, Australia.
Yikai YangAustralian Research Council Training Centre for Innovative BioEngineering, School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Sydney, NSW, Australia.
Christina MaherAustralian Research Council Training Centre for Innovative BioEngineering, School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Sydney, NSW, Australia.
Levin KuhlmannFaculty of Information Technology, Monash University, Melbourne, VIC, Australia.
Alistair McEwanAustralian Research Council Training Centre for Innovative BioEngineering, School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Sydney, NSW, Australia.
Armin NikpourComprehensive Epilepsy Service and Department of Neurology at the Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Omid KaveheiAustralian Research Council Training Centre for Innovative BioEngineering, School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Sydney, NSW, Australia.
Australian Research Council · AUUniversity of Sydney · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epileptic seizure forecasting, combined with the delivery of preventative therapies, holds the potential to greatly improve the quality of life for epilepsy patients and their caregivers. Forecasting seizures could prevent some potentially catastrophic consequences such as injury and death in addition to several potential clinical benefits it may provide for patient care in hospitals. The challenge of seizure forecasting lies within the seemingly unpredictable transitions of brain dynamics into the ictal state. The main body of computational research on determining seizure risk has been focused solely on prediction algorithms, which involves a challenging issue of balancing sensitivity and false alarms. There have been some studies on identifying potential biomarkers for seizure forecasting; however, the questions of "What are the true biomarkers for seizure prediction" or even "Is there a valid biomarker for seizure prediction?" are yet to be fully answered. In this paper, we introduce a tool to facilitate the exploration of the potential biomarkers. We confirm using our tool that interictal slowing activities are a promising biomarker for epileptic seizure susceptibility prediction.

Indexed as

Bayesianepileptic seizure forecastingprobabilistic programminguncertainty levelvariational inference

Identifiers

PMID34589049
PMCPMC8474878
OpenAlexW3200962900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.