Evidence map›Paper›PMID 34589003›Full record

ArticleFrontiers in psychiatry2021

Gut Microbiome: A Potential Indicator for Differential Diagnosis of Major Depressive Disorder and General Anxiety Disorder.

Zaiquan Dong, Xiaoling Shen, Yanni Hao, Jin Li, Haoran Li, Haizheng Xu, Li Yin, Weihong Kuang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 6 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 6 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
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  6. Pooled it
  7. Effects ofFrontiers in psychiatry · 2026
    Trial
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  18. The Gut Microbiome in Anxiety Disorders.Current psychiatry reports · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zaiquan DongMental Health Center of West China Hospital, Sichuan University, Chengdu, China.
Xiaoling ShenMental Health Center of West China Hospital, Sichuan University, Chengdu, China.
Yanni HaoMental Health Center of West China Hospital, Sichuan University, Chengdu, China.
Jin LiMental Health Center of West China Hospital, Sichuan University, Chengdu, China.
Haoran LiMental Health Center of West China Hospital, Sichuan University, Chengdu, China.
Haizheng XuMental Health Center of West China Hospital, Sichuan University, Chengdu, China.
Li YinMental Health Center of West China Hospital, Sichuan University, Chengdu, China.
Weihong KuangMental Health Center of West China Hospital, Sichuan University, Chengdu, China.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

16S ribosomal RNAanxietydepressiondifferential diagnosisgut microbiome

Identifiers

PMID34589003
PMCPMC8473618
OpenAlexW3157812131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.