Evidence map›Paper›PMID 34588809›Full record

Trial reportJournal of pain research2021

High-Frequency Impulse Therapy for Treatment of Chronic Back Pain: A Multicenter Randomized Controlled Pilot Study.

Kasra Amirdelfan, Mindy Hong, Bobby Tay, Surekha Reddy, Vinay Reddy, Michael Yang, Krishn Khanna, Prasad Shirvalkar, Christopher Abrecht, Amitabh Gulati

Abstract readCase ReportsClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of pain research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kasra AmirdelfanIPM Medical Group, Walnut Creek, CA, USA.
Mindy HongHinge Health, San Francisco, CA, USA.ORCID 0000-0003-2755-3812
Bobby TayDepartment of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA.
Surekha ReddySpine and Nerve Diagnostic Center, Roseville, CA, USA.
Vinay ReddySpine and Nerve Diagnostic Center, Roseville, CA, USA.
Michael YangSummit Pain Alliance, Santa Rosa, CA, USA.
Krishn KhannaDepartment of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA.
Prasad ShirvalkarUCSF Weill Institute of Neurosciences University of California San Francisco, San Francisco, CA, USA.
Christopher AbrechtDepartment of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA, USA.
Amitabh GulatiMemorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0003-1654-8639

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeThis study aims to examine high-frequency impulse therapy (HFIT) impact on pain and function among patients undergoing care for chronic low back pain (CLBP).

methodsA pilot randomized-controlled trial of HFIT system versus sham was conducted across 5 orthopedic and pain center sites in California, USA. Thirty-six patients seeking clinical care for CLBP were randomized. Primary outcome was function measured by the Six Minute Walk Test (6MWT). Secondary outcomes were function (Timed Up and Go [TUG] and Oswestry Disability Index [ODI]), pain (Numerical Rating Scale [NRS]), quality of life (Patient Global Impression of Change [PGIC]), and device use. Patients were assessed at baseline and every week for 4 weeks of follow-up. Mann-Whitney

resultsThe average age of subjects was 53.9 ± 15.7 (mean ± SD) years, with 12.1 ± 8.8 years of chronic low back pain. Patients who received an HFIT device had a significantly higher 6MWT score at weeks 2 [Cohen's

conclusionA larger-scale RCT can build on the findings of this study to test whether HFIT is effective in reducing pain and improving function in CLBP patients. This study shows encouraging evidence of functional improvement and reduction in pain in subjects who used HFIT. The efficacy and minimally invasive nature of HFIT is anticipated to substantially improve the management of CLBP patients.

Indexed as

chronic painHFITneuromodulationnoninvasive treatmentpain

Identifiers

PMID34588809
PMCPMC8473565

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.