Evidence map›Paper›PMID 34588775›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease

Prevalence and Characteristics of Individuals with Preserved Ratio Impaired Spirometry (PRISm) and/or Impaired Lung Function in Japan: The OCEAN Study.

Toshihiko Kaise, Eishin Sakihara, Kentaro Tamaki, Hiroaki Miyata, Norimichi Hirahara, Oksana Kirichek, Ryosuke Tawara, Shoko Akiyama, Masayuki Katsumata, Mei Haruya and 4 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Toshihiko KaiseJapan Development, GSK, Tokyo, Japan.ORCID 0000-0001-6059-7900
Eishin SakiharaLifestyle Related Disease Medical Center, Naha Medical Association, Okinawa, Japan.
Kentaro TamakiDepartment of Breast Surgery, Nahanishi Clinic, Okinawa, Japan.
Hiroaki MiyataHealth Policy and Management, School of Medicine, Keio University, Tokyo, Japan.
Norimichi HiraharaHealth Policy and Management, School of Medicine, Keio University, Tokyo, Japan.
Oksana KirichekValue Evidence and Outcomes, GSK, Stockley Park, UK.
Ryosuke TawaraJapan Development, GSK, Tokyo, Japan.ORCID 0000-0003-4308-8260
Shoko AkiyamaJapan Development, GSK, Tokyo, Japan.ORCID 0000-0002-4388-6089
Masayuki KatsumataJapan Development, GSK, Tokyo, Japan.
Mei HaruyaGovernment Affairs and Market Access, GSK, Tokyo, Japan.
Takeo IshiiMedical Japan, GSK, Tokyo, Japan.
Edgar P SimardValue Evidence and Outcomes, GSK, Collegeville, PA, USA.
Bruce E MillerValue Evidence and Outcomes, GSK, Collegeville, PA, USA.ORCID 0000-0003-3904-3182
Ruth Tal-SingerValue Evidence and Outcomes, GSK, Collegeville, PA, USA.ORCID 0000-0002-5275-8062
GlaxoSmithKline (United States) · USKeio University · JPHealth Economics and Outcomes Research (United Kingdom) · GBNagara Medical Center · JPOsaka Nishi Clinic · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMany individuals with obstructive airway disease (OAD), including chronic obstructive pulmonary disease (COPD) and asthma, remain undiagnosed, despite the potential for reducing disease burden through early detection and treatment. OCEAN aimed to determine the prevalence of, and characteristics associated with, impaired lung function in a Japanese population, with the goal of improving strategies for early OAD detection.

methodsOCEAN was an observational, cross-sectional study in sequentially recruited Japanese individuals ≥40 years of age undergoing routine health examinations. Participants completed screening questionnaires and spirometry testing. Airflow limitation was defined as forced expiratory volume in 1 second/forced vital capacity (FEV

resultsOverall, 2518 individuals were included; 79% were <60 years of age (mean 52.0 years). Airflow limitation and PRISm were observed in 52 (2.1%) and 420 (16.7%) participants, respectively. FEV

conclusionA significant proportion of Japanese individuals <60 years of age attending their annual health examination had impaired lung function (airflow limitation and PRISm); prevalence was highest among current smokers. These findings support screening of current or former smokers ≥40 years of age using patient-reported questionnaires to inform the need for spirometry to confirm an OAD diagnosis.

Indexed as

Pulmonary Disease, Chronic ObstructiveCross-Sectional StudiesForced Expiratory VolumeHumansJapanLungMiddle AgedPrevalenceSpirometryVital Capacityairflow limitationCAATCAPTURECOPD-QJapanPRISm

Identifiers

PMID34588775
PMCPMC8476108
OpenAlexW3199940519

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.