Evidence map›Paper›PMID 34588773›Full record

ArticleInternational journal of chronic obstructive pulmonary disease

Impact of Lung Function and Exacerbations on Health-Related Quality of Life in COPD Patients Within One Year: Real-World Analysis Based on Claims Data.

Alisa Stöber, Johanna I Lutter, Larissa Schwarzkopf, Florian Kirsch, Anja Schramm, Claus F Vogelmeier, Reiner Leidl

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Efficacy of Biologics in Patients with Moderate to Very Severe COPD: A Systematic Review.International journal of chronic obstructive pulmonary disease · 2026
    Pooled it
  2. Post-tuberculosis lung impairment: systematic review and meta-analysis of spirometry data from 14 621 people.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  3. Lung function trajectory: a partial mediator of the relationships between depressive symptoms and health-related quality of life in the aging population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Physicians' Knowledge of Pulmonary Rehabilitation in China: A Cross-Sectional Study.International journal of chronic obstructive pulmonary disease · 2024
    Article
  13. Article
  14. Performance of spirometry assessment at TB diagnosis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  15. Article
  16. Factors Associated with the Non-Exacerbator Phenotype of Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2023
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Alisa StöberInstitute of Health Economics and Health Care Management, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0001-6368-0662
Johanna I LutterInstitute of Health Economics and Health Care Management, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-0159-4862
Larissa SchwarzkopfInstitute of Health Economics and Health Care Management, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-9402-7700
Florian KirschInstitute of Health Economics and Health Care Management, Helmholtz Zentrum München, Neuherberg, Germany.
Anja SchrammAOK Bayern, Service Center of Health Care Management, Regensburg, Germany.ORCID 0000-0002-4703-2355
Claus F VogelmeierDepartment of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-University Marburg, Member of the German Center for Lung Research (DZL), Marburg, Germany.
Reiner LeidlInstitute of Health Economics and Health Care Management, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-7115-7510
Helmholtz Zentrum München · DEBayer (Germany) · DEGerman Center for Lung Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeReal-world evidence on the impact of forced expiratory volume in one second (FEV

methodsUsing German claims data and survey data, we classified 3016 COPD patients and analyzed their health status by GOLD groups AB and CD. HRQoL was measured with the disease-specific COPD assessment test (CAT) and the visual analog scale (VAS) from the generic Euro-Qol 5D-5L. We applied change score models to assess associations between changes in FEV

resultsFEV

conclusionFEV

Indexed as

Pulmonary Disease, Chronic ObstructiveForced Expiratory VolumeHumansLungMaleQuality of LifeRespiratory Function TestsCOPDexacerbationforced expiratory volume in 1 secondhealth-related quality of lifelongitudinal studyreal-world evidence

Identifiers

PMID34588773
PMCPMC8473986
OpenAlexW3199123286

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.