Evidence map›Paper›PMID 34588729›Full record

ArticleActa clinica Croatica2021

EVALUATION OF THE RELATIONSHIP OF MPV, RDW AND PVI PARAMETERS WITH DISEASE SEVERITY IN COVID-19 PATIENTS.

Dilek Atik, Hasan Burak Kaya

Registry-linked trialAbstract read
In one paragraph

Article in Acta clinica Croatica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06755658 (RDW), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06755658 active not recruitingnot on this map

RDW (red Cell Distribution Width) and What Has Happened to the Platelets. is There an Association of RDW and Platelet Kinetics (PLTs and MPV/PLT Ratio), with Survival Outcome in Covid -19 Hospitalised Patients?

TypeobservationalSponsorSismanoglio General HospitalRan2021 to 2025Enrolled500ConditionsInfection by SARS-COV-2
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  12. Clinical outcomes at medium-term follow-up of COVID-19.The journal of the Royal College of Physicians of Edinburgh · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dilek AtikDepartment of Emergency Medicine, Yozgat Bozok University, Yozgat, Turkey.
Hasan Burak KayaDepartment of Emergency Medicine, Yozgat Bozok University, Yozgat, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus was first detected in three severe pneumonia cases in Wuhan, China, in December 2019. Studies on red cell distribution width (RDW-CV) and mean platelet volume (MPV) laboratory parameters, which can be examined in complete blood count in COVID-19 patients, are still very limited. However, to the best of our knowledge, there are no studies examining the relationship between platelet volume index (PVI) and disease severity in COVID-19 patients, which was evaluated in this study. The aim of this study was to evaluate the relationship of disease severity in COVID-19 patients with their MPV, RDW, and PVI parameters. The study included 92 COVID-19 patients as a study group and 84 healthy individuals as control group. All laboratory data and radiological images were scanned retrospectively from patient files and hospital information system. Evaluation of the RDW-CV and MPV blood parameters, and PVI measured in COVID-19 patients yielded statistically significant differences according to the disease severity. We suggest that RDW-CV and PVI, evaluated within the scope of the study, may be the parameters that should be considered in the early diagnosis of the disease, from the initial stages of COVID-19. In addition, we think that the RDW-CV and MPV laboratory parameters, as well as PVI, which all are simple, inexpensive and widely used hematologic tests, can be used as important biomarkers in determining COVID-19 severity and mortality.

Indexed as

COVID-19Mean Platelet VolumeErythrocyte IndicesHumansRetrospective StudiesSARS-CoV-2Severity of Illness IndexCOVID-19Disease severityMean platelet volumePlatelet volume indexRed cell distribution width

Identifiers

PMID34588729
PMCPMC8305345

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.