Evidence map›Paper›PMID 34588605›Full record

ArticleExperimental & molecular medicine2021

A human antibody against human endothelin receptor type A that exhibits antitumor potency.

Man-Seok Ju, Hye-Mi Ahn, Seong-Gu Han, Sanghwan Ko, Jung-Hyun Na, Migyeong Jo, Chung Su Lim, Byoung Joon Ko, Yeon Gyu Yu, Won-Kyu Lee and 2 more

Open access · goldAbstract read
In one paragraph

Article in Experimental & molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. A nondestructive membrane engineering method using an amphiphilic polymer.Protein science : a publication of the Protein Society · 2024
    Article
  7. Review
  8. Article
  9. A robust antibody discovery platform for difficult-to-express G protein-coupled receptors.Protein science : a publication of the Protein Society · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Man-Seok Ju *Department of Biomedical Sciences, Graduate School, Korea University, Seoul, 02841, Republic of Korea.
Hye-Mi Ahn *Division of Translational Science, Research Institute, National Cancer Center, Goyang, Gyeonggi-do, 10408, Republic of Korea.
Seong-Gu Han *Biopharmaceutical Chemistry Major, School of Applied Chemistry, Kookmin University, Seoul, 02707, Republic of Korea.
Sanghwan KoDepartment of Biomedical Sciences, Graduate School, Korea University, Seoul, 02841, Republic of Korea.
Jung-Hyun NaDepartment of Pharmaceutical Engineering, Sangji University, Wonju-si, Gangwon-do, 26339, Republic of Korea.
Migyeong JoDepartment of Biomedical Sciences, Graduate School, Korea University, Seoul, 02841, Republic of Korea.
Chung Su LimNew Drug Development Center, Osong Medical Innovation Foundation, Cheongju, Chungcheongbuk-do, 28160, Republic of Korea.
Byoung Joon KoSchool of Biopharmaceutical and Medical Sciences, Sungshin Women's University, Seoul, 02844, Republic of Korea.
Yeon Gyu YuBiopharmaceutical Chemistry Major, School of Applied Chemistry, Kookmin University, Seoul, 02707, Republic of Korea.
Won-Kyu LeeNew Drug Development Center, Osong Medical Innovation Foundation, Cheongju, Chungcheongbuk-do, 28160, Republic of Korea. gre7@kbiohealth.kr.
Youn-Jae KimDivision of Translational Science, Research Institute, National Cancer Center, Goyang, Gyeonggi-do, 10408, Republic of Korea. yjkim@ncc.re.kr.
Sang Taek JungDepartment of Biomedical Sciences, Graduate School, Korea University, Seoul, 02841, Republic of Korea. sjung@korea.ac.kr.ORCID http://orcid.org/0000-0001-7217-979X
Korea University · KRKookmin University · KROsong Medical Innovation Foundation · KRNational Cancer Center · USNational Cancer Center · KRSangji University · KRSungshin Women's University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelin receptor A (ET

Indexed as

AnimalsAntibodies, MonoclonalAntineoplastic Agents, ImmunologicalCell Line, TumorCHO CellsCricetulusDisease Models, AnimalDose-Response Relationship, DrugEndothelin A Receptor AntagonistsEnzyme-Linked Immunosorbent AssayHumansMiceProtein EngineeringReceptor, Endothelin AXenograft Model Antitumor AssaysAntibodies, MonoclonalAntineoplastic Agents, ImmunologicalEndothelin A Receptor AntagonistsReceptor, Endothelin A

Identifiers

PMID34588605
PMCPMC8492878
OpenAlexW3201985088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.