Evidence map›Paper›PMID 34588535›Full record

ArticleScientific reports2021

Development of coronary dysfunction in adult progeny after maternal engineered nanomaterial inhalation during gestation.

Sara B Fournier, Vincent Lam, Michael J Goedken, Laura Fabris, Phoebe A Stapleton

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sara B FournierEnvironmental and Occupational Health Sciences Institute, Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ, 08854, USA.
Vincent LamDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, 160 Frelinghuysen Rd., Piscataway, NJ, 08854, USA.
Michael J GoedkenResearch Pathology Services, Rutgers University, 41 Gordon Road, Piscataway, NJ, 08854, USA.
Laura FabrisDepartment of Material Science and Engineering, School of Engineering, Rutgers University, 607 Taylor Rd., Piscataway, NJ, 08854, USA.
Phoebe A StapletonEnvironmental and Occupational Health Sciences Institute, Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ, 08854, USA. stapleton@eohsi.rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
TRAINING IN EVIRONMENTAL TOXICOLOGYT32ES007148 · NIEHS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI Lauren M Aleksunes · 1987 to 2026
$11.4M
Microvascular mechanisms of growth restriction after environmental toxicant exposureR01ES031285 · NIEHS · RUTGERS, THE STATE UNIV OF N.J. · PI STAPLETON, PHOEBE · 2021 to 2025
$3.5M
Mitochondrial Mechanisms, Microvascular Function, and Gestational NanotoxicologyR00ES024783 · NIEHS · RUTGERS, THE STATE UNIV OF N.J. · PI STAPLETON, PHOEBE · 2017 to 2019
$747k
NIEHS NIH HHS P30 ES005022NIEHS NIH HHS R00 ES024783NIEHS NIH HHS R01 ES031285NIEHS NIH HHS T32 ES007148
6 · The paper itself

Abstract

Maternal exposure to environmental contaminants during pregnancy can profoundly influence the risk of developing cardiovascular disease in adult offspring. Our previous studies have demonstrated impaired cardiovascular health, microvascular reactivity, and cardiac function in fetal and young adult progeny after maternal inhalation of nano-sized titanium dioxide (nano-TiO

Indexed as

Administration, InhalationAir PollutantsAnimalsAnimals, NewbornFemaleHeart DiseasesInhalation ExposureMaleMaternal ExposureNanostructuresPregnancyRatsRats, Sprague-DawleyTitaniumAir PollutantsTitaniumtitanium dioxide

Identifiers

PMID34588535
PMCPMC8481306
OpenAlexW3203746275

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.