Evidence map›Paper›PMID 34588493›Full record

ArticleScientific reports2021

Artificial intelligence-based detection of epimacular membrane from color fundus photographs.

Enhua Shao, Congxin Liu, Lei Wang, Dan Song, Libin Guo, Xuan Yao, Jianhao Xiong, Bin Wang, Yuntao Hu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Enhua Shao *Department of Ophthalmology, Beijing Tisnghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Congxin Liu *Beijing Eaglevision Technology Co., Ltd, Beijing, China.
Lei WangDepartment of Ophthalmology, Beijing Tisnghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Dan SongDepartment of Ophthalmology, Beijing Tisnghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Libin GuoDepartment of Ophthalmology, Beijing Tisnghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Xuan YaoBeijing Eaglevision Technology Co., Ltd, Beijing, China.
Jianhao XiongBeijing Eaglevision Technology Co., Ltd, Beijing, China.
Bin WangBeijing Eaglevision Technology Co., Ltd, Beijing, China.
Yuntao HuDepartment of Ophthalmology, Beijing Tisnghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. ythu@mail.tsinghua.edu.cn.
Beijing Tsinghua Chang Gung Hospital · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epiretinal membrane (ERM) is a common ophthalmological disorder of high prevalence. Its symptoms include metamorphopsia, blurred vision, and decreased visual acuity. Early diagnosis and timely treatment of ERM is crucial to preventing vision loss. Although optical coherence tomography (OCT) is regarded as a de facto standard for ERM diagnosis due to its intuitiveness and high sensitivity, ophthalmoscopic examination or fundus photographs still have the advantages of price and accessibility. Artificial intelligence (AI) has been widely applied in the health care industry for its robust and significant performance in detecting various diseases. In this study, we validated the use of a previously trained deep neural network based-AI model in ERM detection based on color fundus photographs. An independent test set of fundus photographs was labeled by a group of ophthalmologists according to their corresponding OCT images as the gold standard. Then the test set was interpreted by other ophthalmologists and AI model without knowing their OCT results. Compared with manual diagnosis based on fundus photographs alone, the AI model had comparable accuracy (AI model 77.08% vs. integrated manual diagnosis 75.69%, χ

Indexed as

Deep LearningFundus OculiAgedAged, 80 and overDatasets as TopicEpiretinal MembraneFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedOphthalmoscopyPhotographyRetrospective StudiesTomography, Optical Coherence

Identifiers

PMID34588493
PMCPMC8481557
OpenAlexW3204235144

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.