Evidence map›Paper›PMID 34588422›Full record

ArticleTranslational psychiatry2021

Distinct amyloid and tau PET signatures are associated with diverging clinical and imaging trajectories in patients with amnestic syndrome of the hippocampal type.

Julien Lagarde, Pauline Olivieri, Matteo Tonietto, Philippe Gervais, Claude Comtat, Fabien Caillé, Michel Bottlaender, Marie Sarazin

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. How fiber bundle alterations differ in presumed LATE and amnestic Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Julien LagardeDepartment of Neurology of Memory and Language, GHU Paris Psychiatrie & Neurosciences, Paris, France. j.lagarde@ghu-paris.fr.ORCID 0000-0002-2018-261X
Pauline OlivieriDepartment of Neurology of Memory and Language, GHU Paris Psychiatrie & Neurosciences, Paris, France.
Matteo ToniettoUniversité Paris-Saclay, BioMaps, Service Hospitalier Frederic Joliot CEA, CNRS, Inserm, Orsay, France.
Philippe GervaisUniversité Paris-Saclay, BioMaps, Service Hospitalier Frederic Joliot CEA, CNRS, Inserm, Orsay, France.
Claude ComtatUniversité Paris-Saclay, BioMaps, Service Hospitalier Frederic Joliot CEA, CNRS, Inserm, Orsay, France.ORCID 0000-0003-4691-7001
Fabien CailléUniversité Paris-Saclay, BioMaps, Service Hospitalier Frederic Joliot CEA, CNRS, Inserm, Orsay, France.
Michel BottlaenderUniversité Paris-Saclay, BioMaps, Service Hospitalier Frederic Joliot CEA, CNRS, Inserm, Orsay, France.ORCID 0000-0002-2890-3653
Marie SarazinDepartment of Neurology of Memory and Language, GHU Paris Psychiatrie & Neurosciences, Paris, France. m.sarazin@ghu-paris.fr.ORCID 0000-0002-5438-8392
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to investigate the amyloid and tau PET imaging signatures of patients with amnestic syndrome of the hippocampal type (ASHT) and study their clinical and imaging progression according to their initial PET imaging status. Thirty-six patients with a progressive ASHT and 30 controls underwent a complete neuropsychological assessment, 3 T brain MRI, [

Indexed as

Alzheimer DiseaseCognitive DysfunctionAmyloid beta-PeptidesHippocampusHumansMagnetic Resonance ImagingPositron-Emission Tomographytau ProteinsAmyloid beta-Peptidestau Proteins

Identifiers

PMID34588422
PMCPMC8481505
OpenAlexW3203496710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.