ArticleBMJ open2021
Caregiver burden and associated factors among primary caregivers of patients with ALS in home care: a cross-sectional survey study.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Radiation Therapy for Sialorrhea in Patients With Amyotrophic Lateral Sclerosis: A Case Series and Critical Review.Advances in radiation oncology · 2026Article
- Associations influencing quality of life in caregivers of patients with amyotrophic lateral sclerosis: a stress-process model approach.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- The burden of care: Health and wellbeing of informal caregivers of people with amyotrophic lateral sclerosis.Palliative & supportive care · 2026Article
- Caregiver burden and psychosocial outcomes in owners of dogs with chronic paresis and paralysis compared with owners of healthy dogs.Frontiers in veterinary science · 2026Article
- Dementia knowledge and caregiver burden among carers of older adults in rural eastern Uganda.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Association between apathy and caregiver burden in patients with amyotrophic lateral sclerosis: a cross-sectional study.BMJ open · 2024Article
- Amyotrophic Lateral Sclerosis and Its Management during the COVID-19 Pandemic: A Qualitative Study with Thematic Analysis of Patients and Caregivers Who Participated in Self-Help Groups.Behavioral sciences (Basel, Switzerland) · 2023Article
- Analysis of Caregiver Burden Expressed in Social Media Discussions.International journal of environmental research and public health · 2023Article
- Article
- A cross-sectional evaluation of acceptability of an online palliative rehabilitation program for family caregivers of people with amyotrophic lateral sclerosis and cognitive and behavioral impairments.BMC health services research · 2022Article
- Psychological Support for Family Caregivers of Patients With Amyotrophic Lateral Sclerosis at the Time of the Coronavirus Disease 2019 Pandemic: A Pilot Study Using a Telemedicine Approach.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aims to understand the caregiver burden experienced by the primary caregivers of patients with amyotrophic lateral sclerosis (ALS), and to explore the factors influencing caregiver burden.
designA cross-sectional survey design was used.
settingThis study was conducted with ALS inpatients and follow-up outpatients at the neurology department of a tertiary general hospital in Taiyuan, Shanxi, China and their caregivers.
participantsPatients with ALS and their caregivers (N=120 pairs) participated in a face-to-face interview. PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcome measures included the Zarit Burden Interview scores and personal/role burden scores. There were no secondary outcomes.
resultsMultiple linear and logistic regression analyses were performed to examine the factors influencing burden in ALS patient's caregivers. Multiple linear regression showed that caregivers with higher Anxiety Index (AI) experienced greater personal (β=0.089, p<0.001), role (β=0.065, p<0.001) and overall (β=0.200, p<0.001) burden. Logistic regression analysis showed that AI (p=0.025; OR 1.351, 95% CI 1.038 to 1.759) and disease knowledge level (p=0.033; OR 0.305, 95% CI 0.107 to 0.593) are the influencing factors of ALS load classification.
conclusionsHigher AI scores were associated with greater caregiver burden. Caregiver burden of caregivers who had no knowledge of the patient's disease was 0.305 times that of those who had good knowledge. The level of disease knowledge and AI score can serve as key predictors of caregiver burden in ALS.
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