Evidence map›Paper›PMID 34588210›Full record

ArticleDiabetes care2021

The Effect of Discontinuing Continuous Glucose Monitoring in Adults With Type 2 Diabetes Treated With Basal Insulin.

Grazia Aleppo, Roy W Beck, Ryan Bailey, Katrina J Ruedy, Peter Calhoun, Anne L Peters, Rodica Pop-Busui, Athena Philis-Tsimikas, Shichun Bao, Guillermo Umpierrez and 16 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Diabetes care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Observational
  9. The Expanding Role of Continuous Glucose Monitoring in the Management and Prevention of Type 2 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. The role of advanced technologies in improving diabetes outcomes.The American journal of managed care · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 16 institutions in 1 country.

Grazia AleppoFeinberg School of Medicine, Northwestern University, Chicago, IL.
Roy W BeckJaeb Center for Health Research, Tampa, FL rbeck@jaeb.org.ORCID 0000-0002-5194-8446
Ryan BaileyJaeb Center for Health Research, Tampa, FL.
Katrina J RuedyJaeb Center for Health Research, Tampa, FL.
Peter CalhounJaeb Center for Health Research, Tampa, FL.
Anne L PetersKeck School of Medicine of the University of Southern California, Los Angeles, CA.
Rodica Pop-BusuiUniversity of Michigan, Ann Arbor, MI.
Athena Philis-TsimikasScripps Whittier Diabetes Institute, San Diego, CA.
Shichun BaoVanderbilt University Medical Center, Nashville, TN.
Guillermo UmpierrezEmory University School of Medicine, Atlanta, GA.
Georgia DavisEmory University School of Medicine, Atlanta, GA.
Davida KrugerHenry Ford Health System, Detroit, MI.
Anuj BhargavaIowa Diabetes Research, West Des Moines, IA.
Laura YoungUniversity of North Carolina School of Medicine, Chapel Hill, NC.
John B BuseUniversity of North Carolina School of Medicine, Chapel Hill, NC.
Janet B McGillWashington University School of Medicine, St. Louis, MO.
Thomas MartensInternational Diabetes Center, Park Nicollet Internal Medicine, Minneapolis, MN.
Quang T NguyenLas Vegas Endocrinology, Henderson, NV.
Ian OrozcoCarteret Medical Group, Morehead City, NC.
William BiggsAmarillo Medical Specialists, Amarillo, TX.
K Jean LucasDiabetes and Endocrinology Consultants, PC, Morehead City, NC.
William H PolonskyBehavioral Diabetes Institute, San Diego, CA.
David PriceDexcom, Inc., San Diego, CA.
Richard M Bergenstal
MOBILE Study Group
Type 2 Diabetes Basal Insulin Users: The Mobile Study (MOBILE) Study Group:
Jaeb Center for Health Research · USEmory University · USUniversity of North Carolina at Chapel Hill · USPark Nicollet Clinic · USAmarillo College · USCarteret General Hospital · USDexcom (United States) · USHealthPartners · USNorthwestern University · USScripps Whittier Diabetes Institute · USUniversity of Michigan · USUniversity of Southern California · USVanderbilt University Medical Center · USWashington University in St. Louis · USIowa Diabetes and Endocrinology Research Center · USHenry Ford Health System · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Pilot & Feasibility ProgramP30DK124723 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI P Darrell Neufer · 2020 to 2026
$11.0M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
NCATS NIH HHS UL1 TR001422NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK092926NIDDK NIH HHS P30 DK111022NIDDK NIH HHS P30 DK124723
6 · The paper itself

Abstract

objectiveTo explore the effect of discontinuing continuous glucose monitoring (CGM) after 8 months of CGM use in adults with type 2 diabetes treated with basal without bolus insulin. RESEARCH DESIGN AND

methodsThis multicenter trial had an initial randomization to either real-time CGM or blood glucose monitoring (BGM) for 8 months followed by 6 months in which the BGM group continued to use BGM (

resultsIn the group that discontinued CGM, mean time in range (TIR) 70-180 mg/dL, which improved from 38% before initiating CGM to 62% after 8 months of CGM, decreased after discontinuing CGM to 50% at 14 months (mean change from 8 to 14 months -12% [95% CI -21% to -3%],

conclusionsIn adults with type 2 diabetes treated with basal insulin who had been using real-time CGM for 8 months, discontinuing CGM resulted in a loss of about one-half of the initial gain in TIR that had been achieved during CGM use.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2AdultBlood GlucoseBlood Glucose Self-MonitoringGlycated HemoglobinHumansHypoglycemic AgentsInsulinBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulin

Identifiers

PMID34588210
PMCPMC8669539
OpenAlexW3204375546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.