ArticleBMC ophthalmology2021
Optical coherence tomography features and risk of macular hole formation in the fellow eye.
Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 13 citations in OpenAlex.
- Neurosymbolic AI Framework for Explainable Retinal Disease Classification From OCT Images.Translational vision science & technology · 2026Article
- Evaluating deep learning models for classifying OCT images with limited data and noisy labels.Scientific reports · 2024Article
- Vitreoretinal interface abnormalities in fellow eyes of patients with a macular hole.Fujita medical journal · 2024Article
- Deep learning-based algorithm for the detection of idiopathic full thickness macular holes in spectral domain optical coherence tomography.International journal of retina and vitreous · 2024Article
- Macular Structure Characteristics in Unilateral Idiopathic Full-Thickness Macular Hole and the Healthy Fellow Eyes.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2024Article
- OCT-based deep-learning models for the identification of retinal key signs.Scientific reports · 2023Article
- Rates of Fellow Eye Macular Hole Development During Long Term Follow-Up.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the risk of primary macular hole (MH) in the fellow eye, and to evaluate baseline characteristics and optical coherence tomography (OCT) features that precede MH formation in the fellow eye.
methodsA retrospective review of 229 patients treated for primary MH at Stavanger University Hospital, Norway, from January 2008 through December 2018. The patients were categorised into two groups according to subsequent development of MH in the fellow eye. The OCT findings of the two groups were compared, and associated risk factors for MH formation assessed.
resultsTwenty cases of bilateral MH were identified. The overall bilateral disease risk was 8.8% (95% CI, 5.8-13.2%). Two patients were previously operated in the fellow eye, six patients presented with bilateral MH, and 12 patients subsequently developed MH in the fellow eye. The risk of subsequent MH development was 5.7% (95% CI, 3.3-9.8%). Although the extent of posterior vitreous detachment (PVD) tended to be more progressed in the bilateral group compared with the unilateral group, the difference was not statistically significant. In the bilateral group, 41.7% had outer retinal defects vs 6.6% in the unilateral group (p = 0.001), and 33.3% in the bilateral group had intraretinal pseudocysts vs 10.2% in the unilateral group (p = 0.036, not significant after multiple testing correction).
conclusionOuter retinal defects and intraretinal pseudocysts are associated with an increased risk of MH formation in the fellow eye, and complete PVD indicates a decreased risk of MH formation.
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