Evidence map›Paper›PMID 34587626›Full record

ArticleInteractive cardiovascular and thoracic surgery2022

Evaluation of albendazole efficiency and complications in patients with pulmonary hydatid cyst.

Yener Aydin, Ali Bilal Ulas, Ilker Ince, Asli Kalin, Fatma Kesmez Can, Betul Gundogdu, Kamber Kasali, Bugra Kerget, Yasemin Ogul, Atilla Eroglu

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06483880 (The Role of Adjuvant Albendazole After Pulmonary Hydatid Cyst Resection), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06483880 naunknown statusnot on this mapstarted 2024, after this paper: background citation

The Role of Adjuvant Albendazole After Pulmonary Hydatid Cyst Resection: a Randomised Controlled Trial

TypeinterventionalSponsorAin Shams UniversityRan2024 to 2025Enrolled24ConditionsPulmonary Hydatid CystArmsAlbendazole, Placebo
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Current Management of Pulmonary Hydatid Cyst.The Eurasian journal of medicine · 2025
    Article
  9. A Comprehensive Analysis ofPathogens (Basel, Switzerland) · 2025
    Review
  10. Treatment approach in bilateral pulmonary hydatid cysts: analysis of 107 consecutive cases.Indian journal of thoracic and cardiovascular surgery · 2024
    Article
  11. Article
  12. Article
  13. Doubling time in pulmonary and hepatic hydatid cysts.Turk gogus kalp damar cerrahisi dergisi · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Giant pulmonary hydatid cyst causing a mediastinal shift in a child.Revista da Sociedade Brasileira de Medicina Tropical · 2023
    Article
  20. Parasitic lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yener AydinDepartment of Thoracic Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey.ORCID 0000-0001-6523-2572
Ali Bilal UlasDepartment of Thoracic Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey.ORCID 0000-0003-3880-2423
Ilker InceAnesthesiology Clinical Research Office, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Asli KalinNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-4338-3561
Fatma Kesmez CanDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Betul GundogduDepartment of Pathology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Kamber KasaliDepartment of Bioistatistics, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Bugra KergetDepartment of Pulmonary Diseases, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Yasemin OgulDepartment of Medicinal Biochemistry, Regional Training and Research Hospital, Health Sciences University, Erzurum, Turkey.
Atilla ErogluDepartment of Thoracic Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey.ORCID 0000-0003-1357-2676
Atatürk University · TRErzurum Regional Training and Research Hospital · TRUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study investigated the efficacy and complications of albendazole use after surgery in patients with pulmonary hydatid cysts.

methodsOne hundred fifty-three consecutive patients who met the study criteria out of 215 patients who received prophylaxis with albendazole after surgery for isolated pulmonary hydatid cysts in our clinic between January 2011 and December 2020 were analysed retrospectively.

resultsEighty-six out of 153 (56.2%) of cases were male and 67 (43.8%) were female. The average age was 24.6 ± 17.4 (between 3 and 71 years), 76 of them (49.7%) were 18 years old and younger, while 77 (50.3%) were adults. All cases were approached transthoracically and a total of 170 operations were performed on the 153 cases. Fever, weakness and dizziness were reported in only one patient who was given albendazole treatment. A partial increase in liver enzymes was observed in 16 cases (10.5%) after albendazole treatment. Mild leukopoenia and neutropenia were observed in only one of the cases. In 1 case, a second operation was performed 30 months later due to recurrence. Albendazole treatment was not required to be discontinued in any of the cases. Mortality was not observed in any of the cases. Factors such as mean age, cyst size and hospitalization period did not have a statistically significant effect on any changes in liver enzymes tests following albendazole therapy (P > 0.05).

conclusionsAlbendazole treatment can safely be used for postoperative prophylaxis in patients with pulmonary hydatid cysts in a controlled manner without causing serious complications. SUBJ COLLECTION: 152.

Indexed as

AlbendazoleEchinococcosis, HepaticEchinococcosis, PulmonaryAdolescentAdultAgedChildChild, PreschoolFemaleHumansMaleMiddle AgedRetrospective StudiesYoung AdultAlbendazoleAlbendazoleComplicationHydatid cystLungReliability

Identifiers

PMID34587626
PMCPMC8766210
OpenAlexW3202989126

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.