Evidence map›Paper›PMID 34587197›Full record

ArticlePloS one2021

Barriers and facilitators for optimizing oral anticoagulant management: Perspectives of patients, caregivers, and providers.

Anne Holbrook, Mei Wang, Marilyn Swinton, Sue Troyan, Joanne M W Ho, Deborah M Siegal

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anne HolbrookDivision of Clinical Pharmacology and Toxicology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-3371-4187
Mei WangClinical Pharmacology Research, St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.
Marilyn SwintonSchool of Nursing, McMaster University, Hamilton, Ontario, Canada.
Sue TroyanClinical Pharmacology Research, St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.
Joanne M W HoDivision of Geriatric Medicine, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Deborah M SiegalDivision of Hematology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.ORCID 0000-0003-3806-3245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral anticoagulants (OACs) are very commonly prescribed for prevention of serious vascular events, but are also associated with serious medication-related bleeding. Mitigation of harm is believed to require high-quality OAC management. This study aimed to identify barriers and facilitators for optimal OAC management from the perspective of patients, caregivers and healthcare providers.

methodsUsing a qualitative descriptive study design, we conducted five focus groups, three with patients and caregivers and two with health care providers, in two health regions in Southwestern Ontario. An expert facilitator led the discussions using a semi-structured interview guide. Each session was digitally recorded, transcribed verbatim and anonymized. Transcripts were analyzed in duplicate using conventional content analysis.

resultsForty-two (19 patients, 7 caregivers, and 16 providers including physicians, nurses and pharmacists) participated. More than half of the patients received OAC for the treatment of venous thromboembolism (57.9%) and the majority (94.7%) were on chronic therapy (defined as >3 years). Data analysis organized codes describing barriers and facilitators into 4 main themes-medication-related, patient-related, provider-related, and system-related. Barriers highlighted were problems with medication access due to cost, patient difficulties with adherence, knowledge and adjusting their lifestyles to OAC therapy, provider expertise, time for adequate communication amongst providers and their patients, and health care system inadequacies in supporting communications and monitoring. Facilitators identified generally addressed these barriers.

conclusionsMany barriers to optimal OAC management exist even in the era of DOACs, many of which are amenable to facilitators of improved care coordination, patient education, and adherence monitoring.

Indexed as

Administration, OralAdultAgedAnticoagulantsCaregiversFemaleFocus GroupsHealth PersonnelHumansInterviews as TopicMaleMiddle AgedOntarioPatient CompliancePractice Patterns, Physicians'Qualitative ResearchAnticoagulants

Identifiers

PMID34587197
PMCPMC8480846

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.