Evidence map›Paper›PMID 34586914›Full record

ArticleThe British journal of radiology2021

Coronary flow quantification estimated by dynamic 320-detector CT angiography: validation by

Yuka Matsuo, Michinobu Nagao, Atsushi Yamamoto, Kiyoe Ando, Risako Nakao, Kenji Fukushima, Mitsuru Momose, Akiko Sakai, Kayoko Sato, Shuji Sakai

Open access · greenAbstract readValidation Study
In one paragraph

Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yuka MatsuoDepartment of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
Michinobu NagaoDepartment of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
Atsushi YamamotoDepartment of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
Kiyoe AndoDepartment of Nuclear Medicine, Saitama Medical University International Medical Center, Saitama, Japan.
Risako NakaoDepartment of Nuclear Medicine, Saitama Medical University International Medical Center, Saitama, Japan.
Kenji FukushimaDepartment of Nuclear Medicine, Saitama Medical University International Medical Center, Saitama, Japan.
Mitsuru MomoseDepartment of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
Akiko SakaiDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Kayoko SatoDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Shuji SakaiDepartment of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
Tokyo Women's Medical University · JPSaitama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesResting coronary flow index (rCFI) estimated by 320-detector low-dose dynamic coronary CT angiography (CCTA) is a direct flow quantification using intracoronary attenuation. We propose modified-rCFI from new protocol combining dynamic scan and standard CCTA using dose-modulation, and validate its consistency with quantitative values and ischemia depicted by

methods46 patients who underwent dynamic CCTA and NH

resultsrCFI and modified-rCFI had significant positive correlations with stress MBF and MFR. The optical cut-offs of rCFI and modified-rCFI of 0.39 and 0.61 could detect territories with MFR <2.0, with AUCs of 0.75 and 0.73, sensitivities of 48 and 34%, and specificities of 97 and 98%. Optimal cut-offs of rCFI and modified-rCFI distinguished ischemic segments from non-ischemic segments, with AUCs of 0.75 and 0.91, sensitivities of 53 and 50%, and specificities of 93 and 95%.

conclusionTwo types of rCFI correlated with quantitative values from NH ADVANCES IN KNOWLEDGE: rCFI can contribute as additional functional test over standard CCTA in clinical work-up.

Indexed as

AmmoniaNitrogen RadioisotopesAdultAgedAged, 80 and overComputed Tomography AngiographyCoronary AngiographyFemaleFractional Flow Reserve, MyocardialHeartHumansMaleMiddle AgedPositron-Emission TomographyReproducibility of ResultsAmmoniaNitrogen Radioisotopes

Identifiers

PMID34586914
PMCPMC8553190
OpenAlexW3204655703

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.