Evidence map›Paper›PMID 34586810›Full record

ArticleJournal of chemical theory and computation2021

Importance of Anion-π Interactions in RNA GAAA and GGAG Tetraloops: A Combined MD and QM Study.

Reza Esmaeeli, María de Las Nieves Piña, Antonio Frontera, Alberto Pérez, Antonio Bauzá

Abstract readCase Reports
In one paragraph

Article in Journal of chemical theory and computation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Anion-π Catalysis Enabled by the Mechanical Bond.Angewandte Chemie (International ed. in English) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reza EsmaeeliChemistry Department, University of Florida, Gainesville, Florida 32611, United States.
María de Las Nieves PiñaDepartment of Chemistry, Universitat de les Illes Balears, Crta. de Valldemossa km 7.5, 07122 Palma, Baleares, Spain.
Antonio FronteraDepartment of Chemistry, Universitat de les Illes Balears, Crta. de Valldemossa km 7.5, 07122 Palma, Baleares, Spain.ORCID https://orcid.org/0000-0001-7840-2139
Alberto PérezChemistry Department, University of Florida, Gainesville, Florida 32611, United States.
Antonio BauzáDepartment of Chemistry, Universitat de les Illes Balears, Crta. de Valldemossa km 7.5, 07122 Palma, Baleares, Spain.ORCID https://orcid.org/0000-0002-5793-781X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we demonstrate that anion-π interactions (an attractive noncovalent force between electron deficient π-systems and anions) are involved in the stabilization of GAAA and GGAG RNA tetraloops. Using the single recognition particle (SRP)-RNA complexes as a case of study, we combined molecular dynamics (MD) and quantum mechanics (QM) calculations to shed light on the structural influence of phosphate-G anion-π interactions and hydrogen bonds (HBs) involving K

Indexed as

Molecular Dynamics SimulationRNAAnionsHumansHydrogen BondingQuantum TheoryAnionsRNA

Identifiers

PMID34586810
PMCPMC8515804

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.