Evidence map›Paper›PMID 34586721›Full record

ArticleClinical and translational medicine2021

SARS-CoV-2 spike protein alleviates atherosclerosis by suppressing macrophage lipid uptake through regulating R-loop formation on MSR1 mRNA.

Wenting Zhao, Zhen Wang, Wenjing Chen, Miao Chen, Jie Han, Xiang Yin, Xiaotong Hu, Shuai Wang, Jie Zan, Liangrong Zheng

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Wenting ZhaoDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China.
Zhen WangDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China.
Wenjing ChenDepartment of Veterinary Medicine, Institute of Preventive Veterinary Sciences, Zhejiang University College of Animal Sciences, Hangzhou, P. R. China.
Miao ChenDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China.
Jie HanDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China.
Xiang YinDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China.
Xiaotong HuDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China.
Shuai WangDepartment of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, P. R. China.
Jie ZanSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, P. R. China.
Liangrong ZhengDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China.ORCID 0000-0002-3998-1999
First Affiliated Hospital Zhejiang University · CNGuangdong University of Technology · CNWestlake University · CNZhejiang University · CN

Funding

National Key R&D Program of China 2016YFC1301003the Department of Science and Technology, Zhejiang Province LGF19H020011the Department of Science and Technology, Zhejiang Province Z16H020001the Natural Science Foundation of China 81873484
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AtherosclerosisHumansLipid MetabolismMacrophagesR-Loop StructuresRNA, MessengerScavenger Receptors, Class ASpike Glycoprotein, CoronavirusMSR1 protein, humanRNA, MessengerScavenger Receptors, Class ASpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2

Identifiers

PMID34586721
PMCPMC8473477
OpenAlexW3203319302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.