Evidence map›Paper›PMID 34586683›Full record

ArticleJournal of veterinary internal medicine2021

Choledochal stenting for treatment of extrahepatic biliary obstruction in cats.

Maureen A Griffin, William T N Culp, Michelle A Giuffrida, Laura E Selmic, Jordan C Denitz, James A Perry, Alexander C Schoelkopf, Milan Milovancev, Heidi Phillips, Mandy L Wallace and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Surgical Anatomy of the Gastrointestinal Tract in Cats.Animals : an open access journal from MDPI · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Maureen A GriffinUniversity of California-Davis, School of Veterinary Medicine, Davis, California, USA.
William T N CulpUniversity of California-Davis, School of Veterinary Medicine, Davis, California, USA.ORCID https://orcid.org/0000-0001-6132-156X
Michelle A GiuffridaUniversity of California-Davis, School of Veterinary Medicine, Davis, California, USA.
Laura E SelmicOhio State University, College of Veterinary Medicine, Columbus, Ohio, USA.
Jordan C DenitzUniversity of California-Davis, School of Veterinary Medicine, Davis, California, USA.
James A PerryVeterinary Cancer & Surgery Specialists, Milwaukie, Oregon, USA.
Alexander C SchoelkopfVeterinary Cancer & Surgery Specialists, Milwaukie, Oregon, USA.
Milan MilovancevOregon State University, Carlson College of Veterinary Medicine, Corvallis, Oregon, USA.
Heidi PhillipsUniversity of Illinois, College of Veterinary Medicine, Champaign, Illinois, USA.ORCID https://orcid.org/0000-0002-3291-0266
Mandy L WallaceUniversity of Georgia, College of Veterinary Medicine, Athens, Georgia, USA.
Michele A SteffeyUniversity of California-Davis, School of Veterinary Medicine, Davis, California, USA.
Ingrid M BalsaUniversity of California-Davis, School of Veterinary Medicine, Davis, California, USA.
Philipp D MayhewUniversity of California-Davis, School of Veterinary Medicine, Davis, California, USA.
University of California, Davis · USFlorida Cancer Specialists & Research Institute · USGeorgia College & State University · USOregon State University · USThe Ohio State University · USUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited information currently exists regarding the clinical progression and outcomes of cats that undergo choledochal stenting as a treatment for extrahepatic biliary obstruction (EHBO). HYPOTHESIS/

objectivesDescribe clinical characteristics, indications for choledochal stent placement, procedure, and outcomes in a cohort of cats undergoing choledochal stenting and evaluate risk factors associated with survival as well as recurrence of EHBO in affected cats. ANIMALS: Twenty-three client-owned cats undergoing choledochal stent placement.

methodsRetrospective study. Medical records from 6 academic institutions were reviewed, and data were extracted and analyzed statistically.

resultsMedian age of cats was 10.1 years (range, 2-16), and all cats had at least 2 clinical signs. Most common clinical signs were vomiting in 20/22 (90.9%), inappetence in 19/22 (86.4%), and lethargy in 19/23 (82.6%). Procedural complications were uncommon and rarely related to the stenting procedure. Clinical signs improved postoperatively in 15/20 (75.0%) cats and serum total bilirubin concentration decreased postoperatively in 13/19 (68.4%) cats. Eighteen (78.3%) cats survived to discharge. Recurrence of EHBO was documented in 7/18 (38.9%) cats that survived to discharge. Cholelithiasis was associated with recurrence of EHBO. Median survival time for cats that survived to discharge was 931 days (range, 19-3034). Absence of peritoneal effusion was associated with survival to discharge. CONCLUSIONS AND CLINICAL IMPORTANCE: Choledochal stenting was an effective treatment modality in cats with EHBO with few procedural complications and potential for prolonged survival, but substantial risk for recurrence of EHBO was identified.

Indexed as

Cat DiseasesCholestasis, ExtrahepaticAnimalsCatsRetrospective StudiesStentsTreatment Outcomebilirubincommon bile ductgallbladdericterusstent

Identifiers

PMID34586683
PMCPMC8692206
OpenAlexW3201715798

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.