Evidence map›Paper›PMID 34586568›Full record

Observational studyObesity surgery2021

Renal Outcomes 1 Year After Metabolic Bariatric Surgery in a Multi-ethnic Asian Cohort.

Zongwen Wee, Sonali Ganguly, Kwang Wei Tham, Chin Hong Lim, Jeremy Tian Hui Tan, Phong Ching Lee

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Obesity surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zongwen WeeDepartment of Endocrinology, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore. zongwen.wee@mohh.com.sg.ORCID http://orcid.org/0000-0002-6066-3186
Sonali GangulyDepartment of Endocrinology, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.
Kwang Wei ThamSingapore Association for the Study of Obesity, 6 Napier Road #09-17, Singapore, 258449, Singapore.
Chin Hong LimDepartment of Upper Gastrointestinal and Bariatric Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.
Jeremy Tian Hui TanDepartment of Upper Gastrointestinal and Bariatric Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.
Phong Ching LeeDepartment of Endocrinology, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObesity increases the risk of incident chronic kidney disease (CKD) and is one of the strongest risk factors for new-onset CKD even in the absence of metabolic risk factors. Weight loss has been shown to reduce renal hyperfiltration and proteinuria. Metabolic bariatric surgery (MBS) remains an effective treatment for obesity and its metabolic-related complications. However, literature on its impact on renal function remains limited. MATERIALS AND

methodsThis was an observational retrospective study in a tertiary centre in Singapore. MBS cases performed at the centre between 2008 and 2019 were included. The primary outcome measures were estimated glomerular filtration rate (eGFR), calculated using the CKD epidemiology collaboration equation, and albuminuria (defined as urine albumin-creatinine ratio (uACR) > 3.5 mg/mmol) at baseline and 1-year post-MBS.

resultsFive hundred fifty-seven patients were included. One-year post-MBS, median eGFR increased from 110.9 mL/min/1.73 m

conclusionsMBS had a positive impact on renal function with modest but statistically significant improvement in eGFR and reduction in albuminuria at 1-year post-surgery. Longer-term data is required to investigate the durability of this impact.

Indexed as

Bariatric SurgeryObesity, MorbidRenal Insufficiency, ChronicAlbuminuriaCreatinineGlomerular Filtration RateHumansKidneyRetrospective StudiesCreatinineAlbuminuriaChronic kidney diseaseMetabolic bariatric surgeryObesityRenal outcomes

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.