Evidence map›Paper›PMID 34586509›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Late effects in a high-risk population of breast cancer survivors.

Jennifer Y Sheng, Sarah J Skuli, Elissa D Thorner, Nelli Zafman, Carol D Riley, Jessica M Ruck, Katherine C Smith, Claire Snyder, Karen L Smith, Vered Stearns and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jennifer Y ShengSchool of Medicine, The Johns Hopkins University, Baltimore, MD, USA. jsheng7@jhmi.edu.ORCID http://orcid.org/0000-0002-4513-4235
Sarah J SkuliDepartment of Medicine, The Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Elissa D ThornerSidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University, Baltimore, MD, USA.
Nelli ZafmanSidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University, Baltimore, MD, USA.
Carol D RileySidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University, Baltimore, MD, USA.
Jessica M RuckSchool of Medicine, The Johns Hopkins University, Baltimore, MD, USA.
Katherine C SmithSidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University, Baltimore, MD, USA.
Claire SnyderSchool of Medicine, The Johns Hopkins University, Baltimore, MD, USA.
Karen L SmithSchool of Medicine, The Johns Hopkins University, Baltimore, MD, USA.
Vered StearnsSchool of Medicine, The Johns Hopkins University, Baltimore, MD, USA.
Antonio C WolffSchool of Medicine, The Johns Hopkins University, Baltimore, MD, USA.
Johns Hopkins University · USHospital of the University of Pennsylvania · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI WILLIAM George NELSON · 1985 to 2026
$208.6M
National Institutes of Health (US) P30CA006973NCI NIH HHS P30 CA006973Susan G. Komen SAC110053Susan G. Komen SAC170001
6 · The paper itself

Abstract

purposeTo better understand the impact of cancer and treatment on outcomes and guide program development, we evaluated breast cancer survivors at risk for long-term medical and psychosocial issues who participated in survivorship care visits (SVs) at Johns Hopkins Hospital.

methodsWe conducted a prospective survey study of women with stage I-III breast cancer who participated in SVs from 2010-2016. The same 56-item questionnaire administered at SV and follow-up included an assessment of symptoms, social factors, demographics, anxiety, depression, and comorbidities. We added the Godin Exercise questionnaire to the follow-up.

resultsIn 2018, 74 participants were identified as disease-free and mailed a follow-up survey; 52 (70.3%) completed the survey. At a median follow-up time of 3.1 years after diagnosis, participants were less likely to be employed (54% vs. 67%) than at the SV. About two-thirds were sedentary, and this was associated with high body mass index (p = 0.02). Sufficiently active participants (≥ 150 min per week of moderate-intensity activity) were less likely to report pain (p = 0.02) or fatigue (p = 0.001). Although 19% had moderate/severe anxiety or depression at follow-up, participants who reported employment satisfaction were less likely to be depressed (p = 0.02).

conclusionsAwareness of issues faced by survivors is critical for enhancing care and developing models to identify patients who might benefit most from targeted long-term interventions. IMPLICATIONS FOR CANCER SURVIVORS: Interventions to address physical activity, persistent symptoms, and mental health are critical for breast cancer survivors.

Indexed as

Breast NeoplasmsCancer SurvivorsFemaleHumansProspective StudiesQuality of LifeSurvivorsBreast cancerMental healthObesityPatient-reported outcomesPhysical activity

Identifiers

PMID34586509
PMCPMC8732297
OpenAlexW3169703429

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.