Evidence map›Paper›PMID 34586439›Full record

ArticleInternational urogynecology journal2022

Transperineal ultrasound to estimate the appropriate ring pessary size for women with pelvic organ prolapse.

Claudia Manzini, Mariëlla I J Withagen, Frieda van den Noort, Anique T M Grob, Carl H van der Vaart

Open access · hybridAbstract read
In one paragraph

Article in International urogynecology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Automatic identification and segmentation of slice of minimal hiatal dimensions in transperineal ultrasound volumes.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Claudia ManziniDepartment of Obstetrics and Gynecology, University Medical Centre Utrecht, Utrecht, The Netherlands. C.Manzini-2@umcutrecht.nl.ORCID 0000-0002-5265-7915
Mariëlla I J WithagenDepartment of Obstetrics and Gynecology, University Medical Centre Utrecht, Utrecht, The Netherlands.
Frieda van den NoortRobotics and Mechatronics, Faculty of Electrical Engineering Mathematics and Computer Science, Technical Medical Centre, University of Twente, Enschede, The Netherlands.
Anique T M GrobMulti-Modality Medical Imaging, Faculty of Science and Technology, Technical Medical Centre, University of Twente, Enschede, The Netherlands.
Carl H van der VaartDepartment of Obstetrics and Gynecology, University Medical Centre Utrecht, Utrecht, The Netherlands.
University Medical Center Utrecht · NLUniversity of Twente · NL

Funding

Stichting voor de Technische Wetenschappen 15301
6 · The paper itself

Abstract

introduction and hypothesisThe objective was to predict the successful ring pessary size based on the levator hiatal area (HA).

methodsThis is a prospective case-control study. Women with symptomatic pelvic organ prolapse (POP) choosing pessary treatment were included. All women underwent an interview, clinical examination, and 3D/4D transperineal ultrasound (TPUS). The ring pessary size used in each trial and the reason for unsuccessful trials were recorded. In addition, levator hiatal area divided by ring pessary size (HARP ratio) was measured at rest, maximum contraction, and maximum Valsalva. The HARP ratios of successful and unsuccessful trials were compared, receiver operating characteristic curves in the prediction of successful trials were constructed, and the cut-off optimizing sensitivity and specificity was identified.

resultsA total of 162 women were assessed and 106 were included with 77 successful trials, 49 unsuccessful trials owing to dislodgment or failure to relieve POP symptoms, and 20 unsuccessful trials owing to pain/discomfort. Rest HARP ratio and Valsalva HARP ratio were significantly smaller in the successful trials versus dislodgment/failure to relieve POP symptoms trials (mean rest HARP ratio [SD]: 2.93 [0.59] vs 3.24 [0.67], p = 0.021; median Valsalva HARP ratio (IQR): 4.65 (1.56) vs 5.32 (2.08), p = 0.004). No significant difference was observed between pain/discomfort trials and successful trials. The best cut-off for the prediction of successful trials was Valsalva HARP ratio ≤ 5.00.

conclusionsUnsuccessful fitting trials due to dislodgment/failure to relieve POP symptoms are associated with a small ring pessary with respect to the levator HA. A ring pessary that produces a Valsalva HARP ratio > 5.00 has a higher risk of dislodgment/failure to relieve POP symptoms.

Indexed as

Pelvic Organ ProlapsePessariesCase-Control StudiesFemaleHumansPainUltrasonographyLevator avulsionPelvic organ prolapsePessary fittingRing pessary sizeTransperineal ultrasound

Identifiers

PMID34586439
PMCPMC9270306
OpenAlexW3201732603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.