Evidence map›Paper›PMID 34586426›Full record

ArticleDer Internist2022

[Recurrent intracerebral haemorrhage in a 24-year-old female patient].

S Hipp, W von der Emde, C Kulke, M Schlotter, J Schmidt, J Kikhney, A G M Hopf, A Moter, E Eszlari, W Eichinger and 1 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Der Internist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

S HippMedizinische Klinik - Innere Medizin, Klinikum Füssen, Kliniken Ostallgäu-Kaufbeuren, Stadtbleiche 1, 87629, Füssen, Deutschland. stephan.hipp@kliniken-oal-kf.de.
W von der EmdeMedizinische Klinik - Innere Medizin, Klinikum Füssen, Kliniken Ostallgäu-Kaufbeuren, Stadtbleiche 1, 87629, Füssen, Deutschland.
C KulkeRadiologische Praxis Dr. Bauer & Kollegen, Füssen, Deutschland.
M SchlotterKlinik für Neurologie, BKH Kaufbeuren, Kaufbeuren, Deutschland.
J Schmidtm&i-Fachklinik Enzensberg, Hopfen am See, Deutschland.
J KikhneyInstitute for Microbiology, Infectious Diseases, and Immunology, Biofilmcenter, Charité - University Medicine Berlin, Hindenburgdamm 30, 12203, Berlin, Deutschland.
A G M HopfInstitute for Microbiology, Infectious Diseases, and Immunology, Biofilmcenter, Charité - University Medicine Berlin, Hindenburgdamm 30, 12203, Berlin, Deutschland.
A MoterInstitute for Microbiology, Infectious Diseases, and Immunology, Biofilmcenter, Charité - University Medicine Berlin, Hindenburgdamm 30, 12203, Berlin, Deutschland.
E EszlariKlinik für Herzchirurgie, München Klinik Bogenhausen, München, Deutschland.
W EichingerKlinik für Herzchirurgie, München Klinik Bogenhausen, München, Deutschland.
M HinterseerMedizinische Klinik - Innere Medizin, Klinikum Füssen, Kliniken Ostallgäu-Kaufbeuren, Stadtbleiche 1, 87629, Füssen, Deutschland.
München Klinik Bogenhausen · DECharité - Universitätsmedizin Berlin · DECS Diagnostics · DESt. Marien Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 24-year-old female patient from Sierra Leone was referred to the authors' hospital after several unclear intracerebral bleeding events and an echogenic structure on the aortic valve. The patient was receiving oral anticoagulation therapy due to paroxysmal atrial fibrillation and left ventricular noncompaction. Fluorescence in situ hybridization in combination with polymerase chain reaction and sequencing revealed infective endocarditis of the mitral and aortic valve caused by Bartonella quintana. In retrospect, the intracerebral bleeding events could be identified as septic emboli with secondary haemorrhagic transformation under anticoagulation therapy. The patient showed significant clinical improvement and no further bleeding events occurred after receiving biological mitral and aortic valve replacement and several weeks of doxycycline and gentamicin antibiotic therapy.

Indexed as

Bartonella quintanaEndocarditis, BacterialTrench FeverAdultAortic ValveCerebral HemorrhageFemaleHumansIn Situ Hybridization, FluorescenceNeoplasm Recurrence, LocalYoung AdultBartonella quintanaInfective endocarditisIn situ hybridization, fluorescenceLeft ventricular noncompactionTrench fever

Identifiers

PMID34586426
OpenAlexW3204661482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.