ArticleThe Plant cell2021
A transcriptional complex of NGATHA and bHLH transcription factors directs stigma development in Arabidopsis.
Article in The Plant cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 41 citations in OpenAlex.
- A novel role of BPCs in the control of medial domain differentiation during gynoecium development in Arabidopsis thaliana.Plant molecular biology · 2025Article
- Cytokinin-responsive P-type cyclins control Arabidopsis radial style morphology.The Plant journal : for cell and molecular biology · 2025Article
- NGATHA carpel development genes evolved in the common ancestor of seed plants.The Plant journal : for cell and molecular biology · 2025Article
- Fine mapping of the dominant female sterility gene and novel model of hybrid seed production in cabbage (Brassica oleracea L. var. capitata).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Genome-Wide Characterization and Functional Analysis ofPlants (Basel, Switzerland) · 2025Article
- Site-Directed Mutagenesis Mediated by Molecular Modeling and Docking and Its Effect on the Protein-Protein Interactions of the bHLH Transcription Factors SPATULA, HECATE1, and INDEHISCENT.Plants (Basel, Switzerland) · 2025Article
- ROS regulation of stigma papillae growth and maturation in Arabidopsis thaliana.Plant reproduction · 2025Article
- The dynamic regulatory network of stamens and pistils in papaya.BMC plant biology · 2025Article
- Evolution of the basic helix-loop-helix transcription factor SPATULA and its role in gynoecium development.Annals of botany · 2024Article
- Uncoupling FRUITFULL's functions through modification of a protein motif identified by co-ortholog analysis.Nucleic acids research · 2024Article
- Arabidopsis transcription factor TCP4 controls the identity of the apical gynoecium.The Plant cell · 2024Article
- 'Organ'ising Floral Organ Development.Plants (Basel, Switzerland) · 2024Review
- O-glycosylation of the transcription factor SPATULA promotes style development in Arabidopsis.Nature plants · 2024Article
- Rice DSP controls stigma, panicle and tiller primordium initiation.Plant biotechnology journal · 2023Article
- Arabidopsis TCP4 transcription factor inhibits high temperature-induced homeotic conversion of ovules.Nature communications · 2023Article
- Article
- Genome Wide Identification and Annotation of NGATHA Transcription Factor Family in Crop Plants.International journal of molecular sciences · 2022Article
- Comparative transcriptomic analysis of the super hybrid rice Chaoyouqianhao under salt stress.BMC plant biology · 2022Article
- Article
- Systematic Analysis of bHLH Transcription Factors in Cassava Uncovers Their Roles in Postharvest Physiological Deterioration and Cyanogenic Glycosides Biosynthesis.Frontiers in plant science · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The stigma is an angiosperm-specific tissue that is essential for pollination. In the last two decades, several transcription factors with key roles in stigma development in Arabidopsis thaliana have been identified. However, genetic analyses have thus far been unable to unravel the precise regulatory interactions among these transcription factors or the molecular basis for their selective roles in different spatial and temporal domains. Here, we show that the NGATHA (NGA) and HECATE (HEC) transcription factors, which are involved in different developmental processes but are both essential for stigma development, require each other to perform this function. This relationship is likely mediated by their physical interaction in the apical gynoecium. NGA/HEC transcription factors subsequently upregulate INDEHISCENT (IND) and SPATULA and are indispensable for the binding of IND to some of its targets to allow stigma differentiation. Our findings support a nonhierarchical regulatory scenario in which the combinatorial action of different transcription factors provides exquisite temporal and spatial specificity of their developmental outputs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.