ArticleG3 (Bethesda, Md.)2021
Whole-genome assembly of Ganoderma leucocontextum (Ganodermataceae, Fungi) discovered from the Tibetan Plateau of China.
Article in G3 (Bethesda, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- From natural laboratory to drug discovery: Chemical structures, bioactivities, and biosynthesis of meroterpenoids fromChinese herbal medicines · 2026Review
- First pathogenomic insights into Ganoderma ellipsoideum as an emerging causal agent of basal stem rot in oil palm.Scientific reports · 2025Article
- Whole genome sequence of an edible mushroom Strobilomyces alpinus (Boletaceae).G3 (Bethesda, Md.) · 2025Article
- A Review of Genomic, Transcriptomic, and Proteomic Applications in Edible Fungi Biology: Current Status and Future Directions.Journal of fungi (Basel, Switzerland) · 2025Review
- Soil microbial community succession and physicochemical property changes affectFrontiers in microbiology · 2025Article
- Comparative Mitogenomics Provides Valuable Insights for the Phylogeny and New DNA Barcodes ofJournal of fungi (Basel, Switzerland) · 2024Article
- Whole-genome sequencing and comparative genomic analyses of the medicinal fungus Sanguinoderma infundibulare in Ganodermataceae.G3 (Bethesda, Md.) · 2024Article
- Telomere-to-Telomere Genome Assembly of Tibetan Medicinal MushroomJournal of fungi (Basel, Switzerland) · 2023Article
- The putatively high-altitude adaptation of macaque monkeys: Evidence from the fecal metabolome and gut microbiome.Evolutionary applications · 2023Article
- Genome Re-Annotation and Transcriptome Analyses ofJournal of fungi (Basel, Switzerland) · 2023Article
- Whole-Genome Sequencing and Transcriptome Analysis ofJournal of fungi (Basel, Switzerland) · 2022Article
- Phylogenomics and Comparative Genomics Highlight Specific Genetic Features inJournal of fungi (Basel, Switzerland) · 2022Article
- Taxonomy and phylogeny ofFrontiers in microbiology · 2022Article
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15 authors.
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Abstract
Ganoderma leucocontextum, a newly discovered species of Ganodermataceae in China, has diverse pharmacological activities. Ganoderma leucocontextum was widely cultivated in southwest China, but the systematic genetic study has been impeded by the lack of a reference genome. Herein, we present the first whole-genome assembly of G. leucocontextum based on the Illumina and Nanopore platform from high-quality DNA extracted from a monokaryon strain (DH-8). The generated genome was 50.05 Mb in size with an N50 scaffold size of 3.06 Mb, 78,206 coding sequences, and 13,390 putative genes. Genome completeness was assessed using the Benchmarking Universal Single-Copy Orthologs (BUSCO) tool, which identified 96.55% of the 280 Fungi BUSCO genes. Furthermore, differences in functional genes of secondary metabolites (terpenoids) were analyzed between G. leucocontextum and Ganoderma lucidum. Ganoderma leucocontextum has more genes related to terpenoids synthesis compared to G. lucidum, which may be one of the reasons why they exhibit different biological activities. This is the first genome assembly and annotation for G. leucocontextum, which would enrich the toolbox for biological and genetic studies in G. leucocontextum.
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