Evidence map›Paper›PMID 34585950›Full record

ArticleEpigenomics2021

Impact of depression and stress on placental DNA methylation in ethnically diverse pregnant women.

Markos Tesfaye, Suvo Chatterjee, Xuehuo Zeng, Paule Joseph, Fasil Tekola-Ayele

Open access · greenAbstract read
In one paragraph

Article in Epigenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Biomarkers of reproductive psychiatric disorders.The British journal of psychiatry : the journal of mental science · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Placental accelerated aging in antenatal depression.American journal of obstetrics & gynecology MFM · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Markos TesfayeSection of Sensory Science & Metabolism (SenSMet), National Institute on Alcohol Abuse & Alcoholism & National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-3351-701X
Suvo ChatterjeeEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health & Human Development, National Institutes of Health, Bethesda, MD 20892-7004, USA.
Xuehuo ZengDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health & Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Paule JosephSection of Sensory Science & Metabolism (SenSMet), National Institute on Alcohol Abuse & Alcoholism & National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, USA.
Fasil Tekola-AyeleEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health & Human Development, National Institutes of Health, Bethesda, MD 20892-7004, USA.
National Institutes of Health · US

Funding

Sensory Science and Metabolism; Molecular and Neuronal MechanismsZIANR000035 · NINR · NATIONAL INSTITUTE OF NURSING RESEARCH · PI JOSEPH, PAULE · 2018 to 2020
$1.7M
Mechanisms Underlying Individual Variations of Taste and Smell in ObesityZIAAA000135 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI JOSEPH, PAULE · 2021 to 2025
$1.2M
Intramural NIH HHS ZIA NR000035NICHD NIH HHS HHSN275200800002CNICHD NIH HHS HHSN275200800002INICHD NIH HHS HHSN275200800003CNICHD NIH HHS HHSN275200800003INICHD NIH HHS HHSN275200800012CNICHD NIH HHS HHSN275200800013CNICHD NIH HHS HHSN275200800014CNICHD NIH HHS HHSN275200800028CNICHD NIH HHS HHSN275201000009C
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA MethylationEpigenesis, GeneticPregnant PeopleAdultCpG IslandsDepressionFemaleGene Expression ProfilingGene Expression RegulationHumansPlacentaPregnancyQuantitative Trait LociStress, PsychologicalTranscriptomeYoung Adultbiological markersdepressiongene–environmentpostpartumpregnancystress

Identifiers

PMID34585950
PMCPMC8503803
OpenAlexW3202261230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.