ArticleAlcoholism, clinical and experimental research2021
Trajectories of early alcohol use milestones: Interrelations among initiation and progression.
Article in Alcoholism, clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Gonadal Sex and Sex-Chromosome Complement Interact to Affect Ethanol Consumption in Adolescent Four Core Genotypes Mice.Brain sciences · 2026Article
- Longitudinal Associations Between Other-Sex Close Friends and Alcohol Use is a Between-, Not Within-, Person Process.Substance use & misuse · 2026Article
- Reciprocal associations between adolescent extracurricular activity availability and engagement and alcohol-related cognitions and norms: Moderation by socioeconomic status.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- Divergent Pathways Taken in Adolescence Predict Embracing or Resisting Moderate-to-Heavy Drinking in Young Adulthood.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Does alcohol use and related harm differ based on the age of initiation to alcohol? Results from a prospective cohort study.Addiction (Abingdon, England) · 2026Article
- A prospective longitudinal analysis of opioid and stimulant use in American Indian and First Nations communities.Addictive behaviors · 2025Article
- Peer Victimization in Childhood and Timing of Substance Use Initiation: Evidence from a Twin Study.Behavior genetics · 2025Article
- Birth order moderates the association between adverse childhood experiences and externalizing behavior symptoms in adolescence.Journal of experimental child psychology · 2025Article
- Disaggregating Trends in Alcohol Involvement Among Hispanic, Black, and White Female and Male U.S. Adolescents: 2002 to 2019.Journal of studies on alcohol and drugs · 2025Article
- Drinking firsts at home and with parental knowledge: Racial/ethnic differences in associations with later alcohol outcomes among underage youth.Alcohol, clinical & experimental research · 2024Article
- Cross-substance Effects of Adolescent Exposure to Alcohol Content in Popular Movies on Cannabis Initiation.Cannabis (Albuquerque, N.M.) · 2024Article
- The role of parenting in developmental trajectories of risk for adolescent substance use: a bioecological systems cascade model.Frontiers in psychology · 2023Article
- Associations Among Enacted Stigma, Perceived Chances for Success, Life Satisfaction, and Substance Use Among Sexual Minority and Heterosexual Youth.Substance use & misuse · 2023Article
- Adolescent (mis)perceptions of peer alcohol posts on social media: Prospective associations with alcohol attitudes and use.Alcoholism, clinical and experimental research · 2022Article
- Social networking site use and alcohol use behaviors among adolescents: A latent profile analysis.Addictive behaviors · 2022Article
- Grounding alcohol simulation models in empirical and theoretical alcohol research: a model for a Northern Plains population in the United States.System dynamics reviewArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundAlcohol use shows age-graded patterning, with normative use progressing through characteristic milestones of escalating use or severity. Despite some knowledge about the timing of milestone attainment and sequencing across milestones, there is a gap in our understanding of the earliest stages of use. This study characterizes the timing, sequencing, and speed of progression through milestones beginning with the first sip of alcohol.
methodsSixth through eighth graders (N = 1023; 52% female; 76% White; M = 12.23 years old) completed web surveys through the end of high school. Participants reported on alcohol experiences including the first sip, full drink, consumption of 3+ drinks/occasion (heavy drinking), being drunk, and experiencing acute consequences, from which milestone age and speed of progression (duration) were calculated. Milestone prevalence, sequencing, and timing were characterized, and associations between age of attainment and speed of progression were examined. We also examined whether milestone timing and progression varied by sex and racial/ethnic group.
resultsOverall, milestones followed the expected ordering with the exception of heavy drinking (3+ drinks/occasion) and being drunk, which appear to index similar experiences. An earlier age of attainment was associated with an increased likelihood of attaining each of the milestones. In contrast, once a milestone was achieved, there was reduced risk of initiation of subsequent adjacent milestones for individuals with an earlier first sip and full drink, and earlier initiation was associated with a longer duration to subsequent milestones. Girls were more likely to attain all milestones than boys, but there was no sex difference in the age of attainment. In contrast, Hispanic youth reported earlier ages of initiation than White non-Hispanic youth, but the likelihood of attainment did not vary by race/ethnicity. Rapid progression was observed in females but did not vary by race/ethnicity. DISCUSSION: Risks associated with early drinking are complex, with little support for normative ordering of milestones beyond the first sip. Although early drinking is associated with an increased risk of subsequent drinking, it does not appear to place the drinker on an accelerated course to heavier use. A nuanced understanding of risks associated with milestone timing may inform intervention efforts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.