Evidence map›Paper›PMID 34585748›Full record

ArticleAlcoholism, clinical and experimental research2021

Trajectories of early alcohol use milestones: Interrelations among initiation and progression.

Kristina M Jackson, Kristine Marceau, Suzanne M Colby, Nancy P Barnett, Michelle L Rogers, Kerri L Hayes

Abstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristina M JacksonCenter for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA.ORCID 0000-0001-5449-5473
Kristine MarceauHuman Development and Family Studies, Purdue University, West Lafayette, Indiana, USA.
Suzanne M ColbyCenter for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA.ORCID 0000-0003-2027-5936
Nancy P BarnettCenter for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA.ORCID 0000-0001-9634-8287
Michelle L RogersHassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island, USA.
Kerri L HayesCenter for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA.

Funding

Initiation and Progression through Early Drinking Milestones in Underage DrinkersR01AA016838 · NIAAA · BROWN UNIVERSITY · PI JACKSON, KRISTINA MELIA · 2008 to 2018
$6.8M
Bio-behavioral Developmental Origins of Adolescent Substance AbuseK01DA039288 · NIDA · PURDUE UNIVERSITY · PI MARCEAU, KRISTINE · 2016 to 2020
$876k
Developmental Methodology as Applied to Research on Adolescent Alcohol UseK02AA021761 · NIAAA · BROWN UNIVERSITY · PI JACKSON, KRISTINA MELIA · 2013 to 2017
$691k
Longitudinal Methodology and Alcohol UseK01AA013938 · NIAAA · UNIVERSITY OF MISSOURI-COLUMBIA · PI JACKSON, KRISTINA MELIA · 2003 to 2007
$568k
NIAAA NIH HHS K01 AA013938NIAAA NIH HHS K02 AA021761NIAAA NIH HHS R01 AA016838NIDA NIH HHS K01 DA039288
6 · The paper itself

Abstract

backgroundAlcohol use shows age-graded patterning, with normative use progressing through characteristic milestones of escalating use or severity. Despite some knowledge about the timing of milestone attainment and sequencing across milestones, there is a gap in our understanding of the earliest stages of use. This study characterizes the timing, sequencing, and speed of progression through milestones beginning with the first sip of alcohol.

methodsSixth through eighth graders (N = 1023; 52% female; 76% White; M = 12.23 years old) completed web surveys through the end of high school. Participants reported on alcohol experiences including the first sip, full drink, consumption of 3+ drinks/occasion (heavy drinking), being drunk, and experiencing acute consequences, from which milestone age and speed of progression (duration) were calculated. Milestone prevalence, sequencing, and timing were characterized, and associations between age of attainment and speed of progression were examined. We also examined whether milestone timing and progression varied by sex and racial/ethnic group.

resultsOverall, milestones followed the expected ordering with the exception of heavy drinking (3+ drinks/occasion) and being drunk, which appear to index similar experiences. An earlier age of attainment was associated with an increased likelihood of attaining each of the milestones. In contrast, once a milestone was achieved, there was reduced risk of initiation of subsequent adjacent milestones for individuals with an earlier first sip and full drink, and earlier initiation was associated with a longer duration to subsequent milestones. Girls were more likely to attain all milestones than boys, but there was no sex difference in the age of attainment. In contrast, Hispanic youth reported earlier ages of initiation than White non-Hispanic youth, but the likelihood of attainment did not vary by race/ethnicity. Rapid progression was observed in females but did not vary by race/ethnicity. DISCUSSION: Risks associated with early drinking are complex, with little support for normative ordering of milestones beyond the first sip. Although early drinking is associated with an increased risk of subsequent drinking, it does not appear to place the drinker on an accelerated course to heavier use. A nuanced understanding of risks associated with milestone timing may inform intervention efforts.

Indexed as

Risk-TakingAdolescentAdolescent BehaviorAge of OnsetAlcohol DrinkingFemaleHumansMaleRisk FactorsStudentsYoung Adultadolescentalcoholinitiationmilestonessipping

Identifiers

PMID34585748
PMCPMC8642286

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.