Evidence map›Paper›PMID 34585746›Full record

ArticleJournal of medical virology2022

The evaluation of both the expression and serum protein levels of Caspase-3 gene in patients with different degrees of SARS-CoV2 infection.

Pinar Yildiz Gulhan, Recep Eroz, Ozlem Ataoglu, Nevin İnce, Fatih Davran, Cihadiye Elif Öztürk, Zerrin Gamsızkan, Oner Abidin Balbay

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Pinar Yildiz GulhanDepartment of Chest Diseases, Duzce University Medical Faculty, Duzce, Turkey.ORCID 0000-0002-5347-2365
Recep ErozDepartment of Medical Genetics, Duzce University Medical Faculty, Duzce, Turkey.
Ozlem AtaogluDuzce Ataturk State Hospital, Duzce, Turkey.
Nevin İnceDepartment of Infection Diseases, Duzce University Medical Faculty, Duzce, Turkey.
Fatih DavranDepartment of Biochemistry, Duzce University Medical Faculty, Duzce, Turkey.
Cihadiye Elif ÖztürkDepartment of Medical Microbiology, Duzce University Medical Faculty, Duzce, Turkey.
Zerrin GamsızkanDepartment of Family Medicine, Duzce University Medical Faculty, Duzce, Turkey.
Oner Abidin BalbayDepartment of Chest Diseases, Duzce University Medical Faculty, Duzce, Turkey.
Düzce Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the effects of Caspase-3 (CASP3) gene expression and serum levels on preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. A total of 41 individuals (male: 21; female: 20) with SARS-CoV-2 infection were included in the current study. Hemograms were examined from patient blood samples, and CASP3 gene expression levels were detected. Also, human CASP3 levels were determined from the serum samples of patients. The mean age of patients was 56.220 ± 18.937 years. Significant differences were detected among all groups for CASP3

Indexed as

COVID-19AdultAgedCaspase 3C-Reactive ProteinFemaleHumansMaleMiddle AgedRNA, ViralSARS-CoV-2CASP3 protein, humanCaspase 3C-Reactive ProteinRNA, ViralCASP3 genecellular homeostasisSARS-CoV-2

Identifiers

PMID34585746
PMCPMC8662079
OpenAlexW3202178379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.