ArticleCerebral cortex (New York, N.Y. : 1991)2022
Impact of In Utero Exposure to Antiepileptic Drugs on Neonatal Brain Function.
Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Emergence of a synergistic scaffold in the brains of human infants.Communications biology · 2025Article
- Neonatal Electroencephalogram Recording with a Dry Electrode Cap: A Feasibility Study.Sensors (Basel, Switzerland) · 2025Article
- Effect of in utero exposure to antiepileptic drugs on cortical networks and neurophysiological outcomes at 6 years.Epilepsia · 2025Article
- Multiplex dynamic networks in the newborn brain disclose latent links with neurobehavioral phenotypes.Human brain mapping · 2024Article
- Cortical networks show characteristic recruitment patterns after somatosensory stimulation by pneumatically evoked repetitive hand movements in newborn infants.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Networks of cortical activity in infants with epilepsy.Brain communications · 2022Article
- Cortical Cross-Frequency Coupling Is Affected byFrontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In utero brain development underpins brain health across the lifespan but is vulnerable to physiological and pharmacological perturbation. Here, we show that antiepileptic medication during pregnancy impacts on cortical activity during neonatal sleep, a potent indicator of newborn brain health. These effects are evident in frequency-specific functional brain networks and carry prognostic information for later neurodevelopment. Notably, such effects differ between different antiepileptic drugs that suggest neurodevelopmental adversity from exposure to antiepileptic drugs and not maternal epilepsy per se. This work provides translatable bedside metrics of brain health that are sensitive to the effects of antiepileptic drugs on postnatal neurodevelopment and carry direct prognostic value.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.