Evidence map›Paper›PMID 34585668›Full record

ArticleeLife2021

Neural basis for regulation of vasopressin secretion by anticipated disturbances in osmolality.

Angela Kim, Joseph C Madara, Chen Wu, Mark L Andermann, Bradford B Lowell

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  7. Dysregulation of the fluid homeostasis system by aging.bioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Article
  10. NaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Angela KimDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States.ORCID 0000-0002-9475-0798
Joseph C MadaraDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States.
Chen WuDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States.
Mark L AndermannDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States.ORCID 0000-0002-9882-933X
Bradford B LowellDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States.ORCID 0000-0002-0436-3760
Beth Israel Deaconess Medical Center · US

Funding

Transgenic CoreP30DK057521 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KAHN, BARBARA B. · 2000 to 2019
$31.4M
Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI CORKEY, BARBARA E. · 1992 to 2021
$25.0M
The routing of hunger/satiety information by the parabrachial nucleus (PBN)R01DK075632 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BRADFORD B LOWELL · 2006 to 2026
$8.1M
AGRP NEURONS. NMDARs, Spines, Source of Excitatory Input and Downstream EffectorsR01DK096010 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI LOWELL, BRADFORD B · 2012 to 2024
$7.2M
Neurocircuitry Underlying Leptin Regulation of Energy BalanceR01DK089044 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI LOWELL, BRADFORD B · 2010 to 2023
$6.0M
Multiphoton Imaging of Thoughts of Food During Natural and Induced Hunger StatesDP2DK105570 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANDERMANN, MARK L · 2014 to 2014
$2.5M
Neural Pathway Linking Nutritional State To Food-Cue Responses In Insular CortexR01DK109930 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANDERMANN, MARK L · 2016 to 2020
$2.2M
Glutamatergic Neurons in the Arcuate Nucleus (ARC) and Regulation of SatietyR01DK111401 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI LOWELL, BRADFORD B · 2016 to 2020
$2.2M
Identifying the Neural circuit for presystemic control of vasopressin releaseF31DK109575 · NIDDK · HARVARD MEDICAL SCHOOL · PI KIM, ANGELA · 2017 to 2019
$101k
NIDDK NIH HHS DP2 DK105570NIDDK NIH HHS F31 DK109575NIDDK NIH HHS P30 DK046200NIDDK NIH HHS P30 DK057521NIDDK NIH HHS R01 DK075632NIDDK NIH HHS R01 DK089044NIDDK NIH HHS R01 DK096010NIDDK NIH HHS R01 DK109930NIDDK NIH HHS R01 DK111401
6 · The paper itself

Abstract

Water balance, tracked by extracellular osmolality, is regulated by feedback and feedforward mechanisms. Feedback regulation is reactive, occurring as deviations in osmolality are

Indexed as

Osmotic PressureAnimalsArginine VasopressinFemaleHypothalamusMaleMiceNeuronsOsmolar ConcentrationVasopressinsWater-Electrolyte BalanceArginine VasopressinVasopressinsfeedforwardfiber photometrymedicinemouseneuroscienceosmolalitypresystemicvasopressinwater balance

Identifiers

PMID34585668
PMCPMC8601670
OpenAlexW3202496989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.