Evidence map›Paper›PMID 34585593›Full record

ArticleJournal of the American Heart Association2021

Comparison of Transvalvular Aortic Mean Gradients Obtained by Intraprocedural Echocardiography and Invasive Measurement in Balloon and Self-Expanding Transcatheter Valves.

Amr E Abbas, Ramy Mando, Amer Kadri, Houman Khalili, George Hanzel, Francis Shannon, Karim Al-Azizi, Thomas Waggoner, Safwan Kassas, Thomas Pilgrim and 10 more

2 registry-linked trialsAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06753227 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Systematic Assessment of Invasive Versus Echocardiography-derived Transprosthetic Gradients After Transcatheter Aortic Valve Implantation Using Balloon-expandable Transcatheter Heart Valves: the IVEGA-TAVI Study.

Typeobservational_patient_registrySponsorDeutsches Herzzentrum MuenchenRan2024 to 2026Enrolled250ConditionsAORTIC VALVE DISEASES, Aortic Stenosis
NCT07509554 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Investigation of the Relationship Between Changes in Modern Wave-Based Hemodynamic Metrics and Procedural Success or Clinical Improvement in Patients With Severe Aortic Stenosis Following Transcatheter Aortic Valve Replacement (TAVR)

Typeobservational_patient_registrySponsorIstanbul Mehmet Akif Ersoy Educational and Training HospitalRan2026 to 2029Enrolled100ConditionsAortic StenosisArmsTranscatheter aortic valve replacement (TAVR / TAVI)
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Patient Prosthesis Mismatch After SAVR and TAVR.Frontiers in cardiovascular medicine · 2022
    Pooled it
  3. Pooled it
  4. Review
  5. Invasive and echocardiographic gradients of self- and balloon-expandable valves in failing aortic bioprostheses.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026
    Article
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  8. Balloon-Expandable Versus Self-Expanding Valves in Low-Flow, Low-Gradient Aortic Stenosis: Does Valve Type Matter?Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
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  10. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Amr E AbbasBeaumont Hospital Royal Oak Royal Oak MI.ORCID 0000-0002-7316-4247
Ramy MandoBeaumont Hospital Royal Oak Royal Oak MI.ORCID 0000-0002-2727-4648
Amer KadriBeaumont Hospital Royal Oak Royal Oak MI.
Houman KhaliliDelray Medical Center Delray Beach FL.
George HanzelBeaumont Hospital Royal Oak Royal Oak MI.
Francis ShannonBeaumont Hospital Royal Oak Royal Oak MI.
Karim Al-AziziThe Heart Hospital Baylor Plano Plano TX.
Thomas WaggonerPima Heart and Vascular Tucson Medical Center Tucson AZ.
Safwan KassasAscension St. Mary's Hospital Saginaw MI.
Thomas PilgrimBern University Hospital Bern Switzerland.ORCID 0000-0001-8721-4068
Taishi OkunoBern University Hospital Bern Switzerland.
Alexander CamachoMassachusetts General Hospital Boston MA.ORCID 0000-0002-8832-5744
Alexandra SelbergMassachusetts General Hospital Boston MA.ORCID 0000-0002-1540-3772
Sammy ElmariahMassachusetts General Hospital Boston MA.ORCID 0000-0002-8013-8733
Anthony BavryUniversity of Florida Gainesville FL.ORCID 0000-0002-3545-370X
Julien TernacleUniversité Laval/Québec Heart and Lung Institute Québec Canada.ORCID 0000-0002-9629-5864
Jared ChristensenThe Heart Hospital Baylor Plano Plano TX.ORCID 0000-0002-7366-8357
Neil GheewalaPima Heart and Vascular Tucson Medical Center Tucson AZ.
Philippe PibarotUniversité Laval/Québec Heart and Lung Institute Québec Canada.ORCID 0000-0002-3607-279X
Michael MackThe Heart Hospital Baylor Plano Plano TX.ORCID 0000-0002-3148-9158

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Concerns about discordance between echocardiographic and invasive mean gradients after transcatheter aortic valve replacement (TAVR) with balloon-expandable valves (BEVs) versus self-expanding valves (SEVs) exist. Methods and Results In a multicenter study, direct-invasive and echocardiography-derived transvalvular mean gradients obtained before and after TAVR were compared as well as post-TAVR and discharge echocardiographic mean gradients in BEVs versus SEVs in 808 patients. Pre-TAVR, there was good correlation (

Indexed as

Aortic Valve StenosisHeart Valve ProsthesisAortic ValveEchocardiographyHemodynamicsHumansProsthesis DesignTreatment OutcomeBernoulli equationechocardiographic and invasive discordancepressure recoverytranscatheter aortic valve replacement

Identifiers

PMID34585593
PMCPMC8649128

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.