Evidence map›Paper›PMID 34585163›Full record

ArticleSTAR protocols2021

Telomere length assessments of muscle stem cells in rodent and human skeletal muscle sections.

Elisia D Tichy, Foteini Mourkioti

Open access · goldAbstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Elisia D TichyDepartment of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA 19104, USA.
Foteini MourkiotiDepartment of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA 19104, USA.
California Institute for Regenerative Medicine · USUniversity of Pennsylvania · US

Funding

Molecular mechanisms of telomere function in muscle stem cellsR01AR075914 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MOURKIOTI, FOTEINI · 2020 to 2024
$1.9M
Molecular basis of telomere dysfunction in cardiac dystrophyR01HL146662 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MOURKIOTI, FOTEINI · 2019 to 2022
$1.6M
NHLBI NIH HHS R01 HL146662NIAMS NIH HHS R01 AR075914
6 · The paper itself

Abstract

Measurements of telomere length in skeletal muscle stem cells (MuSCs), a rare cell population within muscles, provide insights into cellular dysfunction in diseased conditions. Here, we describe a protocol (cryosection muscle quantitative fluorescent

Indexed as

MyoblastsRodentiaAnimalsHumansMuscle Fibers, SkeletalMuscle, SkeletalTelomereCell-based AssaysCell BiologyCell isolationIn Situ HybridizationMicroscopyStem Cells

Identifiers

PMID34585163
PMCPMC8450295
OpenAlexW3200565569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.