Evidence map›Paper›PMID 34585162›Full record

ArticleSTAR protocols2021

Efficient acquisition of tens of thousands of short tandem repeats in single-cell whole-genome-amplified DNA.

Liming Tao, Zipora Marx, Ofir Raz, Ehud Shapiro

Open access · goldAbstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Liming TaoDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Zipora MarxDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Ofir RazDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Ehud ShapiroDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Weizmann Institute of Science · IL

Funding

Yale SPORE in Skin CancerP50CA121974 · NCI · YALE UNIVERSITY · PI RUTH HALABAN · 2006 to 2026
$43.9M
NCI NIH HHS P50 CA121974
6 · The paper itself

Abstract

Short tandem repeats (STRs) are highly abundant in the human genome, but existing approaches for accurate genotyping of STRs are limited. Here, we describe a protocol for duplex molecular inversion probes for high-throughput and cost-effective STR enrichment. We have successfully tested panels targeting as many as 50K STRs in several thousands of genomic samples (e.g., HeLa cells, Du145 cells, leukemia cells, melanoma cells). However, because the protocol is plate based, the sample size is limited to a few thousand. For complete details on the use and execution of this protocol, please refer to Tao et al. (2021).

Indexed as

Cell Line, TumorGenome, HumanHeLa CellsHigh-Throughput Nucleotide SequencingHumansMicrosatellite RepeatsWhole Genome SequencingGenomicsHigh Throughput ScreeningMolecular BiologyMolecular/Chemical ProbesSequencingSingle Cell

Identifiers

PMID34585162
PMCPMC8452885
OpenAlexW3200624855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.