Evidence map›Paper›PMID 34585089›Full record

ArticleTurkish journal of surgery2021

Acute pancreatitis: predictors of mortality, pancreatic necrosis and intervention.

Ramlal Prajapati, Priyadarshini Manay, Kavin Sugumar, Vinay Rahandale, Rajeev Satoskar

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ramlal PrajapatiDepartment of Surgery, University Hospitals, Seidman Cancer Center, Cleveland, United States.
Priyadarshini ManayDepartment of Transplant Surgery, University of Iowa Hospitals & Clinics, Iowa City, United States.
Kavin SugumarDepartment of Surgery, University Hospitals, Seidman Cancer Center, Cleveland, United States.
Vinay RahandaleDepartment of Surgery, Seth G.S Medical College and King Edward Memorial Hospital, Mumbai, India.
Rajeev SatoskarDepartment of Surgery, Seth G.S Medical College and King Edward Memorial Hospital, Mumbai, India.
King Edward Memorial Hospital and Seth G.S. Medical College · INUniversity Hospitals Seidman Cancer Center · USUniversity of Iowa Hospitals and Clinics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSeveral predictive scoring systems are used in the prognostication of acute pancreatitis (AP). However, the quantity of evidence of these prognostic systems in the Indian population remains sparse. The aim of our study was to evaluate the usefulness of such prognostic scores to predict mortality, incidence of pancreatic necrosis and intervention in AP. MATERIAL AND

methodsThis was an observational study of patients diagnosed with AP between June 2012 and November 2013 in a tertiary referral center in India. Vital signs, biochemical tests and CT-findings were recorded to identify SIRS, Ranson's score and CT-severity index at diagnosis. Chi square test was used to compare incidence of mortality, pancreatic necrosis, and intervention between mild versus severe acute pancreatitis groups.

resultsA total of 100 patients with AP were treated during out study period. Ranson's score more than 7 and presence of pancreatic necrosis were significantly associated with increased mortality (p <0.05). SIRS, CTSI score more than 7, inotropic support, and complications were more frequently associated with patients with necrosis. Prophylactic antibiotics did not decrease mortality, but decreased intervention rate (p <0.05). Presence of systemic inflammatory response syndrome (SIRS), Ranson's score > 7, necrosis, inotropic support and presence of complications were associated with a greater rate of interventions including surgery and percutaneous procedures (p <0.05).

conclusionWe validate SIRS, Ranson's, and CTSI score as prognostic markers for AP in the Indian population. These predictors, when used in combination, can direct early monitoring and aggressive management in order to decrease mortality associated with severe AP.

Indexed as

Acute pancreatitisCT-severity indexnecrosisprognostic scoreRanson’s scoreSIRS

Identifiers

PMID34585089
PMCPMC8448565
OpenAlexW3154571256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.