Evidence map›Paper›PMID 34585051›Full record

ArticleAnnals of gastroenterological surgery2021

Adapted systemic inflammation score as a novel prognostic marker for esophageal squamous cell carcinoma patients.

Daichi Nomoto, Yoshifumi Baba, Takahiko Akiyama, Kazuo Okadome, Masaaki Iwatsuki, Shiro Iwagami, Yuji Miyamoto, Naoya Yoshida, Masayuki Watanabe, Hideo Baba

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Preoperative Low Serum Basophil Levels Predict Poor Prognosis for the Patients with Esophageal Squamous Cell Carcinoma.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026
    Article
  2. Article
  3. Systemic inflammation score as a predictor of death within one year after esophagectomy.Esophagus : official journal of the Japan Esophageal Society · 2024
    Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daichi NomotoDepartment of Gastroenterological Surgery Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Yoshifumi BabaDepartment of Gastroenterological Surgery Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.ORCID https://orcid.org/0000-0003-3657-2388
Takahiko AkiyamaDepartment of Gastroenterological Surgery Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Kazuo OkadomeDepartment of Gastroenterological Surgery Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Masaaki IwatsukiDepartment of Gastroenterological Surgery Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.ORCID https://orcid.org/0000-0002-0886-4618
Shiro IwagamiDepartment of Gastroenterological Surgery Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Yuji MiyamotoDepartment of Gastroenterological Surgery Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.ORCID https://orcid.org/0000-0003-3948-5044
Naoya YoshidaDepartment of Gastroenterological Surgery Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.ORCID https://orcid.org/0000-0002-8447-5278
Masayuki WatanabeDepartment of Gastroenterological Surgery Cancer Institute Hospital Japanese Foundation for Cancer Research Tokyo Japan.ORCID https://orcid.org/0000-0003-0298-1597
Hideo BabaDepartment of Gastroenterological Surgery Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.ORCID https://orcid.org/0000-0002-3474-2550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe adapted systemic inflammation score (aSIS), calculated from serum albumin and the lymphocyte-to-monocyte ratio, has been reported to be a novel prognostic marker for some types of cancers. However, the prognostic impact of aSIS in patients with esophageal squamous cell carcinoma (ESCC) remains controversial. This study aimed to examine the prognostic effects of aSIS in a large cohort of 509 ESCC patients.

methodsPreoperative aSIS was retrospectively calculated for 509 ESCC patients who underwent curative resection. Time-dependent receiver operating characteristics (t-ROC) curves were used for comparing the prognostic impact.

resultsPatients with high aSIS showed significantly poorer overall survival (OS) than patients with low aSIS (log rank

conclusionPreoperative aSIS may be a useful prognostic biomarker in ESCC patients who underwent curative resection.

Indexed as

adapted systemic inflammation scoreesophageal squamous cell carcinomaprognosis

Identifiers

PMID34585051
PMCPMC8452479

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.