ReviewAnnals of gastroenterological surgery2021
Optimal patient selection for successful two-stage hepatectomy of bilateral colorectal liver metastases.
Review in Annals of gastroenterological surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Evolution of two-stage hepatectomy: 25 years of modifications and lessons learned.Hepatobiliary surgery and nutrition · 2026Article
- Augmenting the Future Liver Remnant Prior to Major Hepatectomy: A Review of Options on the Menu.Annals of surgical oncology · 2025Review
- Review
- Laparoscopic versus open right hepatectomy for colorectal liver metastases after portal vein embolization: international multicentre study.The British journal of surgery · 2024Article
- Surgical technique for fully robotic two-stage hepatectomy using indocyanine green fluorescence imaging for bilobar colorectal liver metastases.Journal of visualized surgery · 2024Article
- Solitary colorectal liver metastasis: overview of treatment strategies and role of prognostic factors.Journal of cancer research and clinical oncology · 2022Review
- An Analysis of Clinicopathological Outcomes and the Utility of Preoperative MRI for Patients Undergoing Resection of Mucinous and Non-Mucinous Colorectal Cancer Liver Metastases.Frontiers in oncology · 2022Article
- Optimal patient selection for successful two-stage hepatectomy of bilateral colorectal liver metastases.Annals of gastroenterological surgery · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two-stage hepatectomy (TSH) is one of the specific surgical techniques that can expand the pool of resectable patients with initially unresectable colorectal liver metastases (CRLM). The indication of TSH for CRLM is only bilateral, multinodular disease, which cannot be resected by a single hepatectomy. TSH is nowadays considered an effective treatment for selected patients, with acceptable morbidity/mortality rates and promising long-term outcomes. However, not all eligible patients can benefit from the TSH strategy. One of the most important issues is dropout from the strategy (failure to complete both of the two sequential procedures), because the survival of such patients is drastically worse compared with patients who can complete both stages. Another important issue is the early recurrence rate and subsequent poor survival even after completion of TSH. Thus, the selection of appropriate patients who can really benefit from the TSH strategy is crucial. This review discusses the optimal patient selection for TSH, which should be helpful for the development of treatment strategies for patients with extensive CRLM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.