Evidence map›Paper›PMID 34584939›Full record

ArticleArchives animal breeding2021

Population validation of reproductive gene mutation loci and association with the litter size in Nubian goat.

Sanbao Zhang, Xiaotong Gao, Yuhang Jiang, Yujian Shen, Hongyue Xie, Peng Pan, Yanna Huang, Yingming Wei, Qinyang Jiang

Open access · goldAbstract read
In one paragraph

Article in Archives animal breeding, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Potential Candidate Genes Associated with Litter Size in Goats: A Review.Animals : an open access journal from MDPI · 2025
    Review
  4. Candidate genes associated with reproductive traits in rabbits.Tropical animal health and production · 2024
    Review
  5. Study of Local Black Iraqi Goats Genotypes for theArchives of Razi Institute · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sanbao ZhangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, Guangxi, China.
Xiaotong GaoCollege of Animal Science and Technology, Guangxi University, Nanning 530004, Guangxi, China.
Yuhang JiangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, Guangxi, China.
Yujian ShenCollege of Animal Science and Technology, Guangxi University, Nanning 530004, Guangxi, China.
Hongyue XieCollege of Animal Science and Technology, Guangxi University, Nanning 530004, Guangxi, China.
Peng PanCollege of Animal Science and Technology, Guangxi University, Nanning 530004, Guangxi, China.
Yanna HuangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, Guangxi, China.
Yingming WeiInstitute for New Rural Development, Guangxi University, Nanning 530004, Guangxi, China.
Qinyang JiangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, Guangxi, China.
Guangxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Litter size is an important component trait of doe reproduction. By improving it, production efficiency and economic benefits can be significantly provided. Genetic marker-assisted selection (MAS) based on proven molecular indicators could enhance the efficacy of goat selection, as well as litter size trait. Many molecular markers have been identified that they can be used to improve litter size in different goat breeds. However, the presence and value of these markers vary among goat breeds. In the present study, we used the reported loci on other breeds of goat as candidate loci to detect whether these loci appear in this Nubian goat population; then we proceed to genotype and detect surrounding loci (50 bp) by multiplex PCR and sequencing technology. As a result, 69 mutations (59 SNPs and 10 indels) were screened out from 23 candidate genes in Nubian goat population, 12 loci were significantly associated with the litter size of first-parity individuals; 5 loci were significantly associated with the litter size of second-parity individuals; 3 loci were significantly associated with the litter size of third-parity individuals. In addition, five loci were significantly associated with the average litter size. The additive effect value of

Identifiers

PMID34584939
PMCPMC8461558
OpenAlexW3201064396

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.