Evidence map›Paper›PMID 34584846›Full record

ArticleMolecular genetics and metabolism reports2021

Multiple variants in

Nicole M Tate, Katie M Minor, Jody P Lulich, James R Mickelson, Allyson Berent, Jonathan D Foster, Kasey H Petersen, Eva Furrow

Open access · goldAbstract read
In one paragraph

Article in Molecular genetics and metabolism reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. The hitchhiker's guide to feline xanthinuria.Journal of feline medicine and surgery · 2026
    Review
  3. Clinical and genetic analysis ofFrontiers in genetics · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nicole M TateDepartment of Veterinary Clinical Sciences, University of Minnesota, College of Veterinary Medicine, St. Paul, MN, USA.
Katie M MinorDepartment of Veterinary Clinical Sciences, University of Minnesota, College of Veterinary Medicine, St. Paul, MN, USA.
Jody P LulichDepartment of Veterinary Clinical Sciences, University of Minnesota, College of Veterinary Medicine, St. Paul, MN, USA.
James R MickelsonDepartment of Veterinary Biomedical Sciences, University of Minnesota, College of Veterinary Medicine, St. Paul, MN, USA.
Allyson BerentDepartment of Interventional Radiology, Animal Medical Center, New York, NY, USA.
Jonathan D FosterFriendship Hospital for Animals, Washington, DC, USA.
Kasey H PetersenDepartment of Veterinary Clinical Sciences, University of Minnesota, College of Veterinary Medicine, St. Paul, MN, USA.
Eva FurrowDepartment of Veterinary Clinical Sciences, University of Minnesota, College of Veterinary Medicine, St. Paul, MN, USA.
University of Minnesota · USThe Schwarzman Animal Medical Center · US

Funding

The role of zinc transporters and dietary zinc in calcium oxalate urolithiasisK01OD019912 · OD · UNIVERSITY OF MINNESOTA · PI FURROW, EVA · 2015 to 2021
$760k
NIH HHS K01 OD019912
6 · The paper itself

Abstract

Hereditary xanthinuria is a rare autosomal recessive disease caused by missense and loss of function variants in the xanthine dehydrogenase (

Indexed as

Canine geneticsCKCS, Cavalier King Charles SpanielDACH, DachshundDBVDC, Dog Biomedical Variant Database ConsortiumECS, English Cocker SpanielFFPE, formalin-fixed paraffin-embeddedHereditary xanthinuriaKidney stonesMOCOS, molybdenum cofactor sulfuraseMolybdenum cofactor sulfuraseMT, Manchester TerrierMUC, Minnesota Urolith CenterMX, mixed breedNephrolithiasisOMIM, Online Mendelian Inheritance in ManXanthine dehydrogenaseXDH, xanthine dehydrogenase

Identifiers

PMID34584846
PMCPMC8455477
OpenAlexW3200686058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.